Evidence map›Paper›PMID 36980777›Full record

ReviewCancers2023

Immune Checkpoint Inhibitors and the Kidney: A Focus on Diagnosis and Management for Personalised Medicine.

Elisa Longhitano, Paola Muscolino, Claudia Lo Re, Serena Ausilia Ferrara, Valeria Cernaro, Guido Gembillo, Dalila Tessitore, Desirèe Speranza, Francesco Figura, Mariacarmela Santarpia and 3 more

Open access · goldFull text readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Review
  6. Article
  7. World journal of radiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Elisa LonghitanoUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.ORCID 0000-0002-5222-4431
Paola MuscolinoMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
Claudia Lo ReUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.
Serena Ausilia FerraraUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.
Valeria CernaroUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.ORCID 0000-0003-4396-5032
Guido GembilloUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.ORCID 0000-0003-4823-9910
Dalila TessitoreMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
Desirèe SperanzaMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.ORCID 0009-0005-5108-1052
Francesco FiguraMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
Mariacarmela SantarpiaMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
Nicola SilvestrisMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
Domenico SantoroUnit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G. Martino", University of Messina, 98125 Messina, Italy.ORCID 0000-0002-4279-6559
Tindara FranchinaMedical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, 98125 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunity plays a crucial role in fighting cancer, but tumours can evade the immune system and proliferate and metastasize. Enhancing immune responses is a new challenge in anticancer therapies. In this context, efficacy data are accumulating on immune checkpoint inhibitors and adjuvant therapies for various types of advanced-stage solid tumours. Unfortunately, immune-related adverse events are common. Although infrequent, renal toxicity may occur via several mechanisms and may require temporary or permanent drug suspension, renal biopsy, and/or immunosuppressive treatment. This short review aims to provide a practical approach to the multidisciplinary management of cancer patients with renal toxicity during treatment with immune checkpoint inhibitors.

Indexed as

AKI-ICIcancerCTLA-4ICIsimmune checkpoint inhibitorsirAEPD-1

Identifiers

PMID36980777
PMCPMC10046877
OpenAlexW4353072651

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read27
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.