Evidence map›Paper›PMID 36980771›Full record

ArticleCancers2023

Elevated Baseline Neutrophil Count Correlates with Worse Outcomes in Patients with Muscle-Invasive Bladder Cancer Treated with Chemoradiation.

Sébastien Meunier, Alexandre Frontczak, Loïc Balssa, Julie Blanc, Salim Benhmida, Mandy Pernot, Magali Quivrin, Etienne Martin, Yasser Hammoud, Gilles Créhange and 1 more

Open access · goldFull text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sébastien MeunierDepartment of Radiation Oncology, Centre Georges François Leclerc, 21000 Dijon, France.
Alexandre FrontczakDepartment of Urology, University Hospital of Besançon, 25000 Besançon, France.
Loïc BalssaDepartment of Urology, University Hospital of Besançon, 25000 Besançon, France.
Julie BlancDepartment of Biostatistics, Centre Georges François Leclerc, 21000 Dijon, France.
Salim BenhmidaDepartment of Radiation Oncology, University Hospital of Besançon, 25000 Besançon, France.
Mandy PernotDepartment of Radiation Oncology, University Hospital of Besançon, 25000 Besançon, France.
Magali QuivrinDepartment of Radiation Oncology, Centre Georges François Leclerc, 21000 Dijon, France.
Etienne MartinDepartment of Radiation Oncology, Centre Georges François Leclerc, 21000 Dijon, France.
Yasser HammoudDepartment of Radiation Oncology, University Hospital of Besançon, 25000 Besançon, France.
Gilles CréhangeDepartment of Radiation Oncology, Institut Curie, 92210 Saint-Cloud, France.
Jihane BoustaniDepartment of Radiation Oncology, University Hospital of Besançon, 25000 Besançon, France.
Centre Hospitalier Universitaire de Besançon · FRCentre Georges François Leclerc · FRInserm · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of inflammation in the development and prognosis of bladder cancer (BC) is now established. We evaluated the significance of neutrophil-to-lymphocyte ratio (NLR) and neutrophil count (PNN) in patients with localized BC treated with chemoradiation.

methodsClinical characteristics and baseline biological data were retrospectively collected. We tested the association between NLR, PNN, and overall survival (OS) and progression-free survival (PFS).

resultsOne hundred and ninety-four patients were included. Median PNN was 4000.0/mm

conclusionsElevated PNN at baseline was associated with worse OS and PFS. NLR was not an independent prognostic factor.

Indexed as

chemoradiationinflammationlocalized bladder cancerneutrophil countneutrophil-to-lymphocyte ratio

Identifiers

PMID36980771
PMCPMC10047214
OpenAlexW4328101727

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read56
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.