Evidence map›Paper›PMID 36980760›Full record

ArticleCancers2023

Support Tools in the Differential Diagnosis of Salivary Gland Tumors through Inflammatory Biomarkers and Radiomics Metrics: A Preliminary Study.

Umberto Committeri, Simona Barone, Giovanni Salzano, Antonio Arena, Gerardo Borriello, Francesco Giovacchini, Roberta Fusco, Luigi Angelo Vaira, Alfonso Scarpa, Vincenzo Abbate and 5 more

Open access · goldFull text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Prognostic Significance of Neutrophil-Lymphocyte Ratio in Salivary Gland Neoplasms: A Systematic Review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Pooled it
  3. Observational
  4. Diagnostic value of the pan-immune-inflammation value, plateletcrit, and monocyte count in salivary gland tumors: a 10-year two-stage retrospective analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
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  9. Evaluation of Inflammatory Biomarkers in Parotid Tumors.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Umberto CommitteriMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.
Simona BaroneMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0003-3592-7028
Giovanni SalzanoMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0003-3947-8733
Antonio ArenaMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0003-0903-3733
Gerardo BorrielloMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.
Francesco GiovacchiniDepartment of Maxillo-Facial Medicine Surgery, Hospital of Perugia, 06132 Perugia, Italy.
Roberta FuscoMedical Oncology Division, Igea SpA, 80013 Naples, Italy.
Luigi Angelo VairaMaxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-7789-145X
Alfonso ScarpaDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0001-9219-6175
Vincenzo AbbateMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0002-7905-0531
Lorenzo UggaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80131 Naples, Italy.ORCID 0000-0001-7811-4612
Pasquale PiombinoMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.
Franco IonnaOtolaryngology and Maxillo-Facial Surgery Unit, Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale, 80131 Naples, Italy.
Luigi CalifanoMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.
Giovanni Dell'Aversana OrabonaMaxillofacial Surgery Operative Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy.ORCID 0000-0001-6479-6130
University of Naples Federico II · ITIGEA Clinical Biophysics (Italy) · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of Salerno · ITUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate how the systemic inflammation response index (SIRI), systemic immune-inflammation index (SII), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), and radiomic metrics (quantitative descriptors of image content) extracted from MRI sequences by machine learning increase the efficacy of proper presurgical differentiation between benign and malignant salivary gland tumors.

methodsA retrospective study of 117 patients with salivary gland tumors was conducted between January 2015 and November 2022. Univariate analyses with nonparametric tests and multivariate analyses with machine learning approaches were used.

resultsInflammatory biomarkers showed statistically significant differences (

conclusionsInflammatory biomarkers and radiomic features can comparably support a pre-surgical differential diagnosis.

Indexed as

machine learningneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratioradiomicssalivary gland tumorssystemic immune-inflammation indexsystemic inflammation response index

Identifiers

PMID36980760
PMCPMC10047378
OpenAlexW4328119688

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read14
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.