Evidence map›Paper›PMID 36980664›Full record

ArticleCancers2023

Body Composition of Patients Undergoing Radical Cystectomy for Bladder Cancer: Sarcopenia, Low Psoas Muscle Index, and Myosteatosis Are Independent Risk Factors for Mortality.

Simon U Engelmann, Christoph Pickl, Maximilian Haas, Sebastian Kaelble, Valerie Hartmann, Maximilian Firsching, Laura Lehmann, Miodrag Gužvić, Bas W G van Rhijn, Johannes Breyer and 2 more

Open access · goldFull text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Simon U EngelmannDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Christoph PicklDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Maximilian HaasDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Sebastian KaelbleDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Valerie HartmannDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Maximilian FirschingDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Laura LehmannDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Miodrag GužvićDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.ORCID 0000-0001-8089-3969
Bas W G van RhijnDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Johannes BreyerDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Maximilian BurgerDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
Roman MayrDepartment of Urology, St. Josef Medical Center, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany.
University of Regensburg · DEThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed a wide array of body composition parameters to identify those most relevant as prognostic tools for patients undergoing radical cystectomy (RC) due to bladder cancer (BC).

methodsIn this retrospective, single-center study, preoperative computed tomography (CT) scans of 657 patients were measured at the level of the 3rd lumbar vertebra (L3) to determine common body composition indices including sarcopenia, myosteatosis, psoas muscle index (PMI), subcutaneous and visceral fat index (SFI and VFI), visceral-to-subcutaneous fat ratio (VSR), and visceral obesity. Predictors of overall survival (OS) and cancer-specific survival (CSS) were identified in univariate and multivariate survival analysis.

resultsSarcopenia and a low PMI were independently associated with shorter OS (Sarcopenia: HR 1.30; 95% CI 1.02-1.66;

conclusionsSarcopenia, a low PMI, and myosteatosis are independent predictors for OS and CSS in patients undergoing radical cystectomy for bladder cancer.

Indexed as

bladder cancerbody compositioncachexiacystectomysarcopeniaurothelial carcinoma

Identifiers

PMID36980664
PMCPMC10046300
OpenAlexW4324385612

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.