Evidence map›Paper›PMID 36980663›Full record

ReviewCancers2023

Gastric Cancer with Peritoneal Metastases: Current Status and Prospects for Treatment.

Israel Manzanedo, Fernando Pereira, Estíbalitz Pérez-Viejo, Ángel Serrano

Open access · goldFull text readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Role of surgery in metastatic gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Unaccounted clinical factors in CINV outcomes: the missing role of IO therapy, metastatic sites, and prophylaxis strategy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Israel ManzanedoDepartment of General and Digestive Surgery, Peritoneal Carcinomatosis Unit, Hospital of Fuenlabrada, 28943 Madrid, Spain.ORCID 0000-0003-4188-1740
Fernando PereiraDepartment of General and Digestive Surgery, Peritoneal Carcinomatosis Unit, Hospital of Fuenlabrada, 28943 Madrid, Spain.ORCID 0000-0002-9976-5112
Estíbalitz Pérez-ViejoDepartment of General and Digestive Surgery, Peritoneal Carcinomatosis Unit, Hospital of Fuenlabrada, 28943 Madrid, Spain.ORCID 0000-0002-3407-4628
Ángel SerranoDepartment of General and Digestive Surgery, Peritoneal Carcinomatosis Unit, Hospital of Fuenlabrada, 28943 Madrid, Spain.
Hospital Universitario de Fuenlabrada · ESUniversidad Rey Juan Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) has a poor prognostic and only one in four patients will have survived by 5 years after diagnosis. These poor results are due to the fact that most patients are diagnosed in advanced stages; peritoneal metastases (PM) are especially frequent and are difficult to treat. Currently, PM are considered a terminal stage of GC with a poor survival rate and are treated with palliative systemic chemotherapy. Since the beginning of the century, the treatment of PM from different origins has evolved; cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have become the treatment of choice for many malignant diseases that affect the peritoneum. CRS and HIPEC have also been used for patients with GC and PM, achieving survival results that have never been achieved when using systemic chemotherapy alone. The use of HIPEC can even prevent the development of peritoneal recurrences in patients with locally advanced GC as adjuvant therapy, can reduce the volume of peritoneal disease as neoadjuvant therapy, and can control symptoms in a palliative setting. The aim of this review is to collate the current scientific evidence regarding the treatment of PM of GC origin with surgery and intraperitoneal chemotherapy.

Indexed as

cytoreductive surgerygastric cancerHIPECperitoneal metastases

Identifiers

PMID36980663
PMCPMC10046173
OpenAlexW4324360049

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read55
reference markers read7
identifiers read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.