Evidence map›Paper›PMID 36980591›Full record

ArticleCancers2023

Impact of Molecular Testing Using Next-Generation Sequencing in the Clinical Management of Patients with Non-Small Cell Lung Cancer in a Public Healthcare Hospital.

Javier Simarro, Gema Pérez-Simó, Nuria Mancheño, Emilio Ansotegui, Carlos Francisco Muñoz-Núñez, José Gómez-Codina, Óscar Juan, Sarai Palanca

Open access · goldFull text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Impact ofFrontiers in public health · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Javier SimarroMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0003-3155-1713
Gema Pérez-SimóMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Nuria MancheñoPathology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Emilio AnsoteguiPulmonology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
Carlos Francisco Muñoz-NúñezRadiology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.
José Gómez-CodinaClinical and Translational Cancer Research Group, Instituto de Investigación Sanitaria La Fe (IIS La Fe), 46026 Valencia, Spain.
Óscar JuanMedical Oncology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7772-9030
Sarai PalancaMolecular Biology Unit, Service of Clinical Analysis, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0003-0001-1060
Hospital Universitari i Politècnic La Fe · ESUniversitat de València · ES

Funding

Consellería de Educación, Investigación, Cultura y Deporte de la Comunidad Valenciana ACIF/2018/258Roche Farma IIS La Fe 2015/0713Roche Farma IIS La Fe 2017/0070
6 · The paper itself

Abstract

Next-generation sequencing (NGS) is a molecular approach able to provide a comprehensive molecular profile of non-small cell lung cancer (NSCLC). The broad spectrum of biomarker-guided therapies has positioned molecular diagnostic laboratories as a central component of patient clinical management. Here, we show the results of an UNE-EN ISO 15189:2022 NGS-accredited assay in a cohort of 350 patients.

Indexed as

molecular diagnosisnext-generation sequencingnon-small cell lung cancerquality management systemtranslational research

Identifiers

PMID36980591
PMCPMC10046107
OpenAlexW4324067042

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read43
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.