Evidence map›Paper›PMID 36980487›Full record

ArticleDiagnostics (Basel, Switzerland)2023

National Knowledge-Driven Management of Obstructive Sleep Apnea-The Swedish Approach.

Ludger Grote, Carl-Peter Anderberg, Danielle Friberg, Gert Grundström, Kerstin Hinz, Göran Isaksson, Tarmo Murto, Zarita Nilsson, Jonas Spaak, Göran Stillberg and 5 more

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Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Clinical significance criteria in the ICSD and DSM sleep disorder classifications: a content overlap analysis using the Jaccard index.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  7. Review
  8. Maternal early pregnancy body mass index and risk of sleep apnea in the offspring.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ludger GroteCenter for Sleep and Wake Disorders, Institute of Medicine, Sahlgrenska Academy, Gothenburg University, 405 30 Gothenburg, Sweden.
Carl-Peter AnderbergKvarterskliniken, 411 36 Gothenburg, Sweden.
Danielle FribergDepartment of Otorhinolaryngology, Surgical Sciences, Uppsala University, 752 36 Uppsala, Sweden.ORCID 0000-0001-8327-1292
Gert GrundströmSleep Apnea Patient Organisation (Apne Sverige), 13332 Saltsjoebaden, Sweden.
Kerstin HinzDepartment for Health Care Development, Region of Västra Götaland, 40544 Gothenburg, Sweden.
Göran IsakssonAleris Sleep Apnea Care, 11361 Stockholm, Sweden.
Tarmo MurtoSleep Apnea Unit, Respiratory Medicine, Umeå University Hospital, 90185 Umeå, Sweden.
Zarita NilssonSleep Apnea Unit, ENT Department, Ystad Hospital, 271 82 Ystad, Sweden.
Jonas SpaakDepartment of Cardiology and Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institute, 18288 Danderyd, Sweden.
Göran StillbergSleep Apnea Unit, Capio, 70212 Örebro, Sweden.
Karin SöderbergSleep Apnea Patient Organisation (Apne Sverige), 13332 Saltsjoebaden, Sweden.
Åke TegelbergSleep Apnea Patient Association (Apnefoereningen Syd), 14630 Tullinge, Sweden.
Jenny Theorell-HaglöwFaculty of Odontology, Malmö University, 205 06 Malmö, Sweden.
Martin UlanderDepartment for Clinical Neurophysiology, 58185 Linköping, Sweden.
Jan HednerCenter for Sleep and Wake Disorders, Institute of Medicine, Sahlgrenska Academy, Gothenburg University, 405 30 Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis paper describes the development of "Swedish Guidelines for OSA treatment" and the underlying managed care process. The Apnea Hypopnea Index (AHI) is traditionally used as a single parameter for obstructive sleep apnea (OSA) severity classification, although poorly associated with symptomatology and outcome. We instead implement a novel matrix for shared treatment decisions based on available evidence.

methodsA national expert group including medical and dental specialists, nurses, and patient representatives developed the knowledge-driven management model. A Delphi round was performed amongst experts from all Swedish regions (N = 24). Evidence reflecting treatment effects was extracted from systematic reviews, meta-analyses, and randomized clinical trials.

resultsThe treatment decision in the process includes a matrix with five categories from a "very weak"" to "very strong" indication to treat, and it includes factors with potential influence on outcome, including (A) OSA-related symptoms, (B) cardiometabolic comorbidities, (C) frequency of respiratory events, and (D) age. OSA-related symptoms indicate a strong incitement to treat, whereas the absence of symptoms, age above 65 years, and no or well-controlled comorbidities indicate a weak treatment indication, irrespective of AHI.

conclusionsThe novel treatment matrix is based on the effects of treatments rather than the actual frequency of respiratory events during sleep. A nationwide implementation of this matrix is ongoing, and the outcome is monitored in a prospective evaluation by means of the Swedish Sleep Apnea Registry (SESAR).

Indexed as

CPAPdiagnosisoral devicepositional therapystandardized caretreatment indicationupper airway surgeryweight reduction

Identifiers

PMID36980487
PMCPMC10047173

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.