Evidence map›Paper›PMID 36980464›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Incidence of Air Leaks in Critically Ill Patients with Acute Hypoxemic Respiratory Failure Due to COVID-19.

Robin L Goossen, Mariëlle Verboom, Mariëlle Blacha, Illaa Smesseim, Ludo F M Beenen, David M P van Meenen, Frederique Paulus, Marcus J Schultz, The PRoVENT-Covid And PRoAcT-Covid Investigators

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In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Robin L GoossenDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.
Mariëlle VerboomDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.
Mariëlle BlachaDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.
Illaa SmesseimDepartment of Thoracic Oncology, Antoni van Leeuwenhoek Ziekenhuis, 1066 CX Amsterdam, The Netherlands.
Ludo F M BeenenDepartment of Radiology, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-9204-1026
David M P van MeenenDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.
Frederique PaulusDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.
Marcus J SchultzDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-3969-7792
The PRoVENT-Covid And PRoAcT-Covid Investigators
Amsterdam University Medical Centers · NLMahidol University · THThe Netherlands Cancer Institute · NL

Funding

Netherlands Organisation for Health Research and Development 10430102110008
6 · The paper itself

Abstract

Subcutaneous emphysema, pneumothorax and pneumomediastinum are well-known complications of invasive ventilation in patients with acute hypoxemic respiratory failure. We determined the incidences of air leaks that were visible on available chest images in a cohort of critically ill patients with acute hypoxemic respiratory failure due to coronavirus disease of 2019 (COVID-19) in a single-center cohort in the Netherlands. A total of 712 chest images from 154 patients were re-evaluated by a multidisciplinary team of independent assessors; there was a median of three (2-5) chest radiographs and a median of one (1-2) chest CT scans per patient. The incidences of subcutaneous emphysema, pneumothoraxes and pneumomediastinum present in 13 patients (8.4%) were 4.5%, 4.5%, and 3.9%. The median first day of the presence of an air leak was 18 (2-21) days after arrival in the ICU and 18 (9-22)days after the start of invasive ventilation. We conclude that the incidence of air leaks was high in this cohort of COVID-19 patients, but it was fairly comparable with what was previously reported in patients with acute hypoxemic respiratory failure in the pre-COVID-19 era.

Indexed as

acute hypoxemic respiratory failureacute respiratory failureair leaksARDSbarotraumachest tubeCOVID-19high-flow nasal oxygeninvasive ventilationpneumomediastinumpneumothoraxpositive pressure ventilationsubcutaneous emphysema

Identifiers

PMID36980464
PMCPMC10046975
OpenAlexW4327972739

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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identifiers read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.