Evidence map›Paper›PMID 36980446›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Ultrasound-Guided Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analyses.

King Hei Stanley Lam, Yung-Tsan Wu, Kenneth Dean Reeves, Felice Galluccio, Abdallah El-Sayed Allam, Philip W H Peng

4 registry-linked trialsOpen access · goldFull text readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06243848 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Ultrasound-Guided Injection With Traditional Median Nerve Decompression Surgery in Patients With Carpal Tunnel Syndrome: Randomized Controlled Study

TypeinterventionalSponsorAfyonkarahisar Health Sciences UniversityRan2024 to 2026Enrolled60ConditionsMusculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided InjectionArmsMinimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
NCT06329960 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Efficacy of Ultrasound-guided Dorsal Scapular Nerve Injection Combined With Rhomboideus Muscle Needle Release

TypeinterventionalSponsorPeking University People's HospitalRan2024 to 2024Enrolled30ConditionsDorsal Scapular Nerve EntrapmentArmsUltrasound-guided injection combined with needle release
NCT06697392 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Ultrasound-based Artificial Intelligence for Grading of Carpal Tunnel Syndrome, a Multicenter Study in China

TypeobservationalSponsorPeking University People's HospitalRan2024 to 2026Enrolled500ConditionsCarpal Tunnel Syndrome (CTS), Ultrasound, Artificial Intelligence (AI)Armsultrasound examination
NCT07334964 nacompletednot on this mapstarted 2025, after this paper: background citation

Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method - A Pilot, Comparative, Randomized Study

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2025 to 2026Enrolled21ConditionsCarpal Tunnel SyndromeArmsCarpal tunnel injection
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Review
  5. Review
  6. The Role of Ultrasound Across the Continuum of Care for Carpal Tunnel Syndrome.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
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  12. Review
  13. Current Surgical Trends in Carpal Tunnel Syndrome.Archives of plastic surgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 7 countries.

King Hei Stanley LamThe Department of Clinical Research, The Hong Kong Institute of Musculoskeletal Medicine, Hong Kong.ORCID 0000-0003-1392-829X
Yung-Tsan WuDepartment of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0003-1175-7909
Kenneth Dean ReevesPrivate Practice PM&R and Pain Management, 4840 El Monte, Roeland Park, KS 66205, USA.ORCID 0000-0002-2346-2326
Felice GalluccioCenter for Regional Anesthesia and Pain Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-7485-471X
Abdallah El-Sayed AllamMorphological Madrid Research Center (MoMaRC), 10107 Madrid, Spain.ORCID 0000-0002-7432-1793
Philip W H PengDepartment of Anesthesiology and Pain Medicine, The University of Toronto, Toronto, ON M5T 2S8, Canada.
Chinese University of Hong Kong · HKPain Management Institute · USTanta University · EGTri-Service General Hospital · TWUnidades Centrales Científico-Técnicas · ESUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carpal tunnel syndrome (CTS) is the most common peripheral entrapment, and recently, ultrasound-guided perineural injection (UPIT) and percutaneous flexor retinaculum release (UPCTR) have been utilized to treat CTS. However, no systematic review or meta-analysis has included both intervention types of ultrasound-guided interventions for CTS. Therefore, we performed this review using four databases (i.e., PubMed, EMBASE, Scopus, and Cochrane) to evaluate the quality of evidence, effectiveness, and safety of the published studies on ultrasound-guided interventions in CTS. Among sixty studies selected for systemic review, 20 randomized treatment comparison or controlled studies were included in six meta-analyses. Steroid UPIT with ultrasound guidance outperformed that with landmark guidance. UPIT with higher-dose steroids outperformed that with lower-dose steroids. UPIT with 5% dextrose in water (D5W) outperformed control injection and hydrodissection with high-volume D5W was superior to that with low-volume D5W. UPIT with platelet-rich plasma outperformed various control treatments. UPCTR outperformed open surgery in terms of symptom improvement but not functional improvement. No serious adverse events were reported in the studies reviewed. The findings suggest that both UPIT and UPCTR may provide clinically important benefits and appear safe. Further treatment comparison studies are required to determine comparative therapeutic efficacy.

Indexed as

carpal tunnel syndromeinjectioninterventionreleaseultrasound-guided

Identifiers

PMID36980446
PMCPMC10046938
OpenAlexW4327730984

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read53
measurements read47
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.