Evidence map›Paper›PMID 36980410›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Impact of Suspected Preterm Labor during Pregnancy on Cardiometabolic Profile and Neurodevelopment during Childhood: A Prospective Cohort Study Protocol.

Jesús González, Marina Vilella, Sonia Ruiz, Iris Iglesia, Marcos Clavero-Adell, Ariadna Ayerza-Casas, Angel Matute-Llorente, Daniel Oros, Jose Antonio Casajús, Victoria Pueyo and 2 more

Open access · goldFull text read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Jesús GonzálezPediatrics Department, Quirónsalud Hospital Zaragoza, 50006 Zaragoza, Spain.
Marina VilellaInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.
Sonia RuizInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.
Iris IglesiaInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-2219-3646
Marcos Clavero-AdellInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.
Ariadna Ayerza-CasasInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-0023-8137
Angel Matute-LlorenteInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0001-8500-1667
Daniel OrosInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.
Jose Antonio CasajúsInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-7215-6931
Victoria PueyoInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-1777-0349
Gerardo RodriguezInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-7985-9912
Cristina PaulesInstituto de Investigación Sanitaria Aragón (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0001-6795-0367
Universidad de Zaragoza · ESInstituto de Investigación Sanitaria Aragón · ESHospital Quirónsalud Barcelona · ESHospital Universitario Miguel Servet · ESInstituto de Salud Carlos III · ES

Funding

Instituto de Salud Carlos III CM20/00171Instituto de Salud Carlos III (JR19/00006)Instituto de Salud Carlos III PI20/00741Instituto de Salud Carlos III RD21/0012/0012
6 · The paper itself

Abstract

introductionSuspected preterm labor (SPL), defined as the presence of regular and painful uterine contractions and cervical shortening, represents a prenatal insult with potential long-term consequences. However, despite recent evidence demonstrating suboptimal neurodevelopment at 2 years in this population, it remains underestimated as a significant risk factor for neurodevelopmental disorders or other chronic diseases. The aim of this study is to assess the impact of suspected preterm labor during pregnancy on cardiometabolic profile and neurodevelopment during childhood (6-8 years). METHODS AND ANALYSIS: Prospective cohort study including children whose mothers suffered suspected preterm labour during pregnancy and paired controls. Neurodevelopmental, cardiovascular, and metabolic assessments will be performed at 6-8 years of age. A trained psychologist will carry out the neurodevelopment assessment including intelligence, visual perception, and behavioral assessment. Body composition and physical fitness assessment will be performed by one trained pediatrician and nurse. Finally, cardiovascular evaluation, including echocardiography and blood pressure, will be performed by two pediatric cardiologists. Data regarding perinatal and postnatal characteristics, diet, lifestyle, and weekly screen time of the child will be obtained from medical history and direct interviews with families. Primary outcome measures will include body mass index and adiposity, percentage of fat mass and total and regional lean mass, bone mineral content and density, cardiorespiratory resistance, isometric muscle strength, dynamic lower body strength, systolic and diastolic blood pressure, left ventricle (LV) systolic and diastolic function, general intelligence index, visuospatial working memory span, oculomotor control test, index of emotional, and behavioral problems.

Indexed as

cardiometabolic profilefetal programmingneurodevelopmentpreterm birthsuspected preterm labor

Identifiers

PMID36980410
PMCPMC10047113
OpenAlexW4324382663

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read11
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.