Evidence map›Paper›PMID 36980354›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Potential of Urine Biomarkers CHI3L1, NGAL, TIMP-2, IGFBP7, and Combinations as Complementary Diagnostic Tools for Acute Kidney Injury after Pediatric Cardiac Surgery: A Prospective Cohort Study.

Wim Vandenberghe, Jorien De Loor, Katrien Francois, Kristof Vandekerckhove, Ingrid Herck, Johan Vande Walle, Harlinde Peperstraete, Thierry Bové, Daniël De Wolf, Lieve Nuytinck and 3 more

Open access · goldFull text read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Advances in Nephrology.Diagnostics (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Wim VandenbergheDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-5464-7940
Jorien De LoorDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Katrien FrancoisDepartment of Cardiac Surgery, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Kristof VandekerckhoveDepartment of Pediatric Cardiology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Ingrid HerckDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Johan Vande WalleDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-9700-5358
Harlinde PeperstraeteDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-5435-1752
Thierry BovéDepartment of Cardiac Surgery, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-3786-0699
Daniël De WolfDepartment of Pediatric Cardiology, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-0846-8914
Lieve NuytinckHealth, Innovation and Research Institute UZ Gent, Ghent University Hospital, 9000 Ghent, Belgium.
Jan J De WaeleDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-1017-9748
Evelyne MeyerLaboratory of Biochemistry, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine, Ghent University, 9000 Ghent, Belgium.
Eric A J HosteDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-9301-8055
Ghent University Hospital · BEGhent University · BE

Funding

Ghent University F2012/IOF-Advanced/001
6 · The paper itself

Abstract

Acute kidney injury (AKI) is common after pediatric cardiac surgery (CS). Several urine biomarkers have been validated to detect AKI earlier. The objective of this study was to evaluate urine CHI3L1, NGAL, TIMP-2, IGFBP7, and NephroCheck

Indexed as

AKIcardiac surgerypediatricurine biomarker

Identifiers

PMID36980354
PMCPMC10047361
OpenAlexW4323852309

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read36
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.