Evidence map›Paper›PMID 36980329›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Respiratory Variations of Central Venous Pressure as Indices of Pleural Pressure Swings: A Narrative Review.

Michele Umbrello, Sergio Cereghini, Stefano Muttini

Full text readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michele UmbrelloSC Terapia Intensiva Neurochirurgica, ASST Santi Paolo e Carlo Polo Universitario, Ospedale San Carlo Borromeo, Via Pio II, 3, 20151 Milano, Italy.ORCID 0000-0003-4356-3543
Sergio CereghiniSC Terapia Intensiva Neurochirurgica, ASST Santi Paolo e Carlo Polo Universitario, Ospedale San Carlo Borromeo, Via Pio II, 3, 20151 Milano, Italy.
Stefano MuttiniSC Terapia Intensiva Neurochirurgica, ASST Santi Paolo e Carlo Polo Universitario, Ospedale San Carlo Borromeo, Via Pio II, 3, 20151 Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The measurement of pleural (or intrathoracic) pressure is a key element for a proper setting of mechanical ventilator assistance as both under- and over-assistance may cause detrimental effects on both the lungs and the diaphragm. Esophageal pressure (Pes) is the gold standard tool for such measurements; however, it is invasive and seldom used in daily practice, and easier, bedside-available tools that allow for rapid and continuous monitoring are greatly needed. The tidal swing of central venous pressure (CVP) has long been proposed as a surrogate for pleural pressure (Ppl); however, despite the wide availability of central venous catheters, this variable is very often overlooked in critically ill patients. In the present narrative review, the physiological basis for the use of CVP waveforms to estimate Ppl is presented; the findings of previous and recent papers that addressed this topic are systematically reviewed, and the studies are divided into those reporting positive findings (i.e., CVP was found to be a reliable estimate of Pes or Ppl) and those reporting negative findings. Both the strength and pitfalls of this approach are highlighted, and the current knowledge gaps and direction for future research are delineated.

Indexed as

central venous pressurecritically ill patientsesophageal pressureinspiratory effortlung mechanicspleural pressure

Identifiers

PMID36980329
PMCPMC10047347

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.