ReviewCells2023
Adult and Pediatric Nail Unit Melanoma: Epidemiology, Diagnosis, and Treatment.
Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Amelanotic subungual melanoma mimicking a glomus tumor: A diagnostic pitfall requiring thumb amputation.JAAD case reports · 2026Article
- Clipping towards clarity: Significant role of simple nail clipping in the diagnosis of nail unit melanoma.JAAD case reports · 2026Article
- Intraoperative Nail Matrix Assessment in Longitudinal Melanonychia.International journal of dermatology · 2026Article
- Longitudinal Melanonychia in Children: Clinical and Histopathologic Features and Management with Literature Update.Dermatopathology (Basel, Switzerland) · 2026Review
- Challenges in the Diagnosis and Management of Nail Melanocytic Disorders.Clinical, cosmetic and investigational dermatology · 2026Review
- Review
- Clinical Characteristics of Nail Unit Melanoma in Türkiye: The Experience of Two Tertiary Dermatology Centers.Balkan medical journal · 2025Article
- Multivariate analysis and prediction model construction for distant metastasis of Acral Melanoma.American journal of cancer research · 2025Article
- Rare subungual amelanotic melanoma presenting as prolonged swelling and exudation after trauma: case report and literature review.Frontiers in immunology · 2025Review
- Transverse V-Y advancement composite tissue flap for repairing defects after longitudinal melanonychia excision-a retrospective cohort study.Frontiers in surgery · 2025Article
- New Insights in Paediatric Dermatopathology-2nd Edition.Dermatopathology (Basel, Switzerland) · 2024Article
- Article
- A rare and challenging case of amelanotic subungual melanoma from Syria.Melanoma management · 2024Article
- Brunelli (Dorsoulnar) Flap for the Reconstruction of Defect of the Thumb Nail Unit After Oncological Resections With Mohs Micrographic Surgery.Plastic and reconstructive surgery. Global open · 2024Article
- Pediatric Nail Disorders.Skin appendage disorders · 2024Review
- Is Raman Spectroscopy of Fingernails a Promising Tool for Diagnosing Systemic and Dermatological Diseases in Adult and Pediatric Populations?Medicina (Kaunas, Lithuania) · 2024Review
- PAK1 and Therapy Resistance in Melanoma.Cells · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nail unit melanoma (NUM) is an uncommon form of melanoma and is often diagnosed at later stages. Approximately two-thirds of NUMs are present clinically as longitudinal melanonychia, but longitudinal melanonychia has a broad differential diagnosis. Clinical examination and dermoscopy are valuable for identifying nail findings concerning malignancy, but a biopsy with histopathology is necessary to confirm a diagnosis of NUM. Surgical treatment options for NUM include en bloc excision, digit amputation, and Mohs micrographic surgery. Newer treatments for advanced NUM include targeted and immune systemic therapies. NUM in pediatric patients is extremely rare and diagnosis is challenging since both qualitative and quantitative parameters have only been studied in adults. There is currently no consensus on management in children; for less concerning melanonychia, some physicians recommend close follow-up. However, some dermatologists argue that the "wait and see" approach can cause delayed diagnosis. This article serves to enhance the familiarity of NUM by highlighting its etiology, clinical presentations, diagnosis, and treatment options in both adults and children.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.