Evidence map›Paper›PMID 36980284›Full record

ArticleCells2023

The Molecular Mechanism of the TEAD1 Gene and miR-410-5p Affect Embryonic Skeletal Muscle Development: A miRNA-Mediated ceRNA Network Analysis.

Wenping Hu, Xinyue Wang, Yazhen Bi, Jingjing Bao, Mingyu Shang, Li Zhang

Open access · goldFull text read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenping HuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-8962-7541
Xinyue WangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-8025-1760
Yazhen BiInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Jingjing BaoInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Mingyu ShangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Li ZhangInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-1197-843X
Chinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle development is a complex biological process involving an intricate network of multiple factor interactions. Through the analysis of transcriptome data and molecular biology confirmation, this study aims to reveal the molecular mechanism underlying sheep embryonic skeletal muscle development. The RNA sequencing of embryos was conducted, and microRNA (miRNA)-mediated competitive endogenous RNA (ceRNA) networks were constructed. qRT-PCR, siRNA knockdown, CCK-8 assay, scratch assay, and dual luciferase assay were used to carry out gene function identification. Through the analysis of the ceRNA networks, three miRNAs (miR-493-3p, miR-3959-3p, and miR-410-5p) and three genes (

Indexed as

MicroRNAsMuscle, SkeletalTEA Domain Transcription FactorsAnimalsGene Expression ProfilingRNA, MessengerRNA, Small InterferingSheepTranscriptomeMicroRNAsRNA, MessengerRNA, Small InterferingTEA Domain Transcription FactorsceRNA networkmiR-410-5psheepskeletal muscleTEAD1 gene

Identifiers

PMID36980284
PMCPMC10047409
OpenAlexW4327953928

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read25
table measurements read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.