Evidence map›Paper›PMID 36980200›Full record

ReviewCells2023

Application of 3D Printing in Bone Grafts.

Adam Brachet, Aleksandra Bełżek, Daria Furtak, Zuzanna Geworgjan, Dawid Tulej, Kinga Kulczycka, Robert Karpiński, Marcin Maciejewski, Jacek Baj

Registry-linked trialFull text readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06792864 (Effectiveness of 3D Printed Polycaprolactone and Tricalcium Phosphate Bone Scaffold for Bone Regeneration in Cranioplasty), which is not on this map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06792864 phase3enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Effectiveness of 3D Printed Polycaprolactone and Tricalcium Phosphate Bone Scaffold for Bone Regeneration in Cranioplasty: Randomized Clinical Trial

TypeinterventionalSponsorUniversidad Austral de ChileRan2024 to 2025Enrolled8ConditionsCranioplasty, Craniotomy, Craniotomy Clipping, Craniotomy SurgeryArmsOsteoprintCR, SMAR SET GMV Endurance Gentamicin
3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Bone organoids and mitochondrial reprogramming.Journal of orthopaedic translation · 2026
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adam BrachetStudent Scientific Group, Department of Forensic Medicine, Medical University of Lublin, ul. Jaczewskiego 9b, 20-090 Lublin, Poland.ORCID 0000-0002-7223-2500
Aleksandra BełżekStudent Scientific Group, Department of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
Daria FurtakStudent Scientific Group, Department of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
Zuzanna GeworgjanStudent Scientific Group, Department of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
Dawid TulejStudent Scientific Group, Department of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
Kinga KulczyckaInstitute of Health Sciences, John Paul II Catholic University of Lublin, 20-708 Lublin, Poland.
Robert KarpińskiDepartment of Machine Design and Mechatronics, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland.ORCID 0000-0003-4063-8503
Marcin MaciejewskiDepartment of Electronics and Information Technology, Faculty of Electrical Engineering and Computer Science, Lublin University of Technology, 20-618 Lublin, Poland.
Jacek BajDepartment of Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of 3D printing in bone grafts is gaining in importance and is becoming more and more popular. The choice of the method has a direct impact on the preparation of the patient for surgery, the probability of rejection of the transplant, and many other complications. The aim of the article is to discuss methods of bone grafting and to compare these methods. This review of literature is based on a selective literature search of the PubMed and Web of Science databases from 2001 to 2022 using the search terms "bone graft", "bone transplant", and "3D printing". In addition, we also reviewed non-medical literature related to materials used for 3D printing. There are several methods of bone grafting, such as a demineralized bone matrix, cancellous allograft, nonvascular cortical allograft, osteoarticular allograft, osteochondral allograft, vascularized allograft, and an autogenic transplant using a bone substitute. Currently, autogenous grafting, which involves removing the patient's bone from an area of low aesthetic importance, is referred to as the gold standard. 3D printing enables using a variety of materials. 3D technology is being applied to bone tissue engineering much more often. It allows for the treatment of bone defects thanks to the creation of a porous scaffold with adequate mechanical strength and favorable macro- and microstructures. Bone tissue engineering is an innovative approach that can be used to repair multiple bone defects in the process of transplantation. In this process, biomaterials are a very important factor in supporting regenerative cells and the regeneration of tissue. We have years of research ahead of us; however, it is certain that 3D printing is the future of transplant medicine.

Indexed as

Biocompatible MaterialsBone TransplantationBone and BonesHumansPrinting, Three-DimensionalTissue EngineeringBiocompatible Materials3D printingbone graftscellsFDMscaffold

Identifiers

PMID36980200
PMCPMC10047278

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.