Evidence map›Paper›PMID 36980188›Full record

ArticleCells2023

A De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy.

Agathe Marcelot, Felipe Rodriguez-Tirado, Philippe Cuniasse, Mei-Ling Joiner, Simona Miron, Alexey A Soshnev, Mimi Fang, Miles A Pufall, Katherine D Mathews, Steven A Moore and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. CRM-1 Aggravates Stroke Injury by Promoting BANF1-Mediated Unfolded Protein Response Through Inducing Nuclear Export of ALKBH5.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Lipodystrophic Laminopathies: From Dunnigan Disease to Progeroid Syndromes.International journal of molecular sciences · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Agathe MarcelotInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette, France.
Felipe Rodriguez-TiradoDepartment of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-6554-8187
Philippe CuniasseInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette, France.
Mei-Ling JoinerDepartment of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Simona MironInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette, France.
Alexey A SoshnevDepartment of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Mimi FangDepartment of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Miles A PufallDepartment of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Katherine D MathewsDepartment of Pediatrics and Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Steven A MooreWellstone Muscular Dystrophy Specialized Research Center, Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-6353-7900
Sophie Zinn-JustinInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette, France.ORCID 0000-0002-7680-1088
Pamela K GeyerDepartment of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-9275-1407
University of Iowa · USCentre National de la Recherche Scientifique · FRThe University of Texas at San Antonio · US

Funding

Muscular Dystrophy Specialized Research Center: Project 2P50NS053672 · NINDS · UNIVERSITY OF IOWA · PI KEVIN P. CAMPBELL · 2020 to 2026
$11.9M
Role of novel onco-histone mutations in B-cell malignanciesR01CA234561 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CESARMAN, ETHEL · 2019 to 2023
$3.3M
The Role of LEM Domain Proteins in Nuclear FunctionR01GM087341 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K. · 2010 to 2022
$2.8M
Aging and the nuclear lamina in mitotic stem cellsR21AG072397 · NIA · UNIVERSITY OF IOWA · PI GEYER, PAMELA K. · 2021 to 2022
$425k
NCI NIH HHS R01 CA234561NIA NIH HHS R21 AG072397NIGMS NIH HHS R01 GM087341NINDS NIH HHS P50 NS053672
6 · The paper itself

Abstract

Barrier-to-autointegration factor (BAF) is an essential component of the nuclear lamina. Encoded by

Indexed as

Cell NucleusNuclear ProteinsChromatinDNA-Binding ProteinsFibrinogenHumansChromatinDNA-Binding ProteinsFibrinogenNuclear ProteinsBarrier-to-autointegration factorDNA bindingemerinhuman variantsmotor neuropathyNéstor–Guillermo progeria syndromenuclear lamina

Identifiers

PMID36980188
PMCPMC10099716
OpenAlexW4323664358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.