Evidence map›Paper›PMID 36980130›Full record

ReviewChildren (Basel, Switzerland)2023

Physical Activity as a Treatment for Cancer-Related Fatigue in Children, Adolescents and Young Adults: A Systematic Review.

Mareike Kuehn, Lena Wypyrsczyk, Sandra Stoessel, Marie A Neu, Lisa Ploch, Elias Dreismickenbecker, Perikles Simon, Joerg Faber

Open access · goldFull text readReview
In one paragraph

Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mareike KuehnCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.ORCID 0000-0003-1906-949X
Lena WypyrsczykCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7928-3872
Sandra StoesselCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Marie A NeuCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Lisa PlochCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Elias DreismickenbeckerCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Perikles SimonInstitute of Sport Science, Department Sport Medicine, Rehabilitation and Disease Prevention, Johannes Gutenberg University, 55128 Mainz, Germany.ORCID 0000-0002-7996-4034
Joerg FaberCenter for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-5432-8234
Johannes Gutenberg University Mainz · DE

Funding

European Union 945153
6 · The paper itself

Abstract

backgroundCancer-related fatigue (CRF) is one of the most common and distressing symptoms in paediatric oncology. Based on previous studies, physical activity interventions are considered to be effective in reducing CRF in adult cancer patients.

aimThe aim of this systematic review is to investigate whether physical activity interventions can reduce CRF in paediatric patients undergoing cancer treatment. METHODOLOGY: A systematic literature search was conducted in PubMed and Sport-Discus in October 2021 to identify intervention studies examining the effects of physical activity on CRF in cancer patients ≤ 21 years of age. Their methodological quality was assessed using the JBI Critical Appraisal Tool.

resultsA total of 20 studies (seven randomized-controlled, six quasi-experimental and seven single-arm intervention trials) were included in the review. Nine studies reported significant positive effects of physical activity interventions on CRF in group comparison or within groups. Eleven trials reported no significant changes in CRF.

conclusionPhysical activity as a therapeutic intervention in paediatric oncology may have the potential to reduce CRF in childhood cancer patients undergoing cancer treatment. Further high-quality studies with large samples are needed to verify these results and to assess the interdependence of dose and response of physical activity interventions.

Indexed as

cancer-related fatiguechildhood cancerexercisephysical activitysystematic review

Identifiers

PMID36980130
PMCPMC10047895
OpenAlexW4327741087

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read15
measurements read12
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.