ArticleChildren (Basel, Switzerland)2023
Overshoot of the Respiratory Exchange Ratio during Recovery from Maximal Exercise Testing in Young Patients with Congenital Heart Disease.
Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Respiratory exchange ratio overshoot during exercise recovery: a promising prognostic marker in HFrEF.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Cardiopulmonary Recovery After Maximal Exercise in Individuals with Neuromuscular Disease and Limited Mobility.Journal of clinical medicine · 2025Article
- Wearable Hyperspectral Photoplethysmography Allows Continuous Monitoring of Exercise-Induced Hypertension.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The Role of Cardiovascular Imaging in the Diagnosis of Athlete's Heart: Navigating the Shades of Grey.Journal of imaging · 2024Review
- Practical Aspects of Cardiopulmonary Exercise Testing in Children.International journal of sports medicine · 2024Review
- Athlete's Heart: A Cardiovascular Step-By-Step Multimodality Approach.Reviews in cardiovascular medicine · 2023Review
- Advances in the Diagnosis and Management of Congenital Heart Disease in Children.Children (Basel, Switzerland) · 2023Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe overshoot of the respiratory exchange ratio (RER) after exercise is reduced in patients with heart failure.
aimThe present study aimed to investigate the presence of this phenomenon in young patients with congenital heart disease (CHD), who generally present reduced cardiorespiratory fitness.
methodsIn this retrospective study, patients with CHD underwent a maximal cardiopulmonary exercise testing (CPET) assessing the RER recovery parameters: the RER at peak exercise, the maximum RER value reached during recovery, the magnitude of the RER overshoot and the linear slope of the RER increase after the end of the exercise.
resultsIn total, 117 patients were included in this study. Of these, there were 24 healthy age-matched control subjects and 93 young patients with CHD (transposition of great arteries, Fontan procedure, aortic coarctation and tetralogy of Fallot). All patients presented a RER overshoot during recovery. Patients with CHD showed reduced aerobic capacity and cardiorespiratory efficiency during exercise, as well as a lower RER overshoot when compared to controls. RER magnitude was higher in the controls and patients with aortic coarctation when compared to those with transposition of great arteries, previous Fontan procedure, and tetralogy of Fallot. The RER magnitude was found to be correlated with the most relevant cardiorespiratory fitness and efficiency indices.
conclusionsThe present study proposes new recovery indices for functional evaluation in patients with CHD. Thus, the RER recovery overshoots analysis should be part of routine CPET evaluation to further improve prognostic risk stratifications in patients with CHD.
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