ReviewChildren (Basel, Switzerland)2023
Neuropsychological Outcomes of Children Treated for Brain Tumors.
Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Executive Function Outcomes in Pediatric Central Nervous System Tumor Survivors.Actas espanolas de psiquiatria · 2026Pooled it
- Long-term neurocognitive and behavioral outcomes in survivors of pediatric brain tumors: a systematic review.Frontiers in neuroscience · 2025Pooled it
- Health-related quality of life in children and adolescents with paediatric acquired brain injury: Secondary data analysis from a randomised controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Trial
- Cognitive complaints and their associations with role functioning limitations among adolescent and young adult cancer survivors in Hong Kong.Asia-Pacific journal of oncology nursing · 2026Article
- Health-Related Quality of Life in Children with Acute Leukaemia and Central Nervous System Tumours: Current Evidence and Future Directions.Children (Basel, Switzerland) · 2026Review
- Sleep-related symptoms and cognitive fatigue are prominent in the multidimensional symptom network of children with malignant solid tumors: key targets and subgroup differences.BMC psychology · 2026Article
- Executive function after childhood cancer: Insights from network neuroscience.Neuro-oncology advances · 2026Review
- Neurobiological and psychological indicators of post-traumatic stress symptoms in children and adolescents treated for a posterior fossa brain tumour.Neuroimage. Reports · 2026Article
- Developmental Foundations of Psychosocial Interventions in Pediatric Oncology: A Lifespan Framework for Resilience.Children (Basel, Switzerland) · 2026Review
- Childhood cancer survivors' struggle for social integration after treatment a mixed-methods exploration of activity and participation.PloS one · 2026Article
- Dual-ligand curcin-loaded hybrid solid lipid nanoparticles achieve durable gliosarcoma remission while preserving neuro-behavioral function.Theranostics · 2026Article
- Criteria for unmet need in paediatric populations and their families: a literature-based case study in haematological malignancies in upper-middle and high-income countries.Frontiers in pediatrics · 2026Review
- Physical Therapy Is an Underutilized Health Resource for Children with Cancer: A Retrospective Study Identifies Facilitators for Improvement.Healthcare (Basel, Switzerland) · 2025Article
- Smart exercise in pediatric oncology: enhancing executive functions through cognitively challenging physical activity- a non-randomized controlled trial.BMC cancer · 2025Article
- Impact of radiation dose on neurocognitive function and quality of life in long-term survivors of childhood brain tumour.Acta oncologica (Stockholm, Sweden) · 2025Article
- A FastSurfer Database for Age-Specific Brain Volumes in Healthy Children: A Tool for Quantifying Localized and Global Brain Volume Alterations in Pediatric Patients.Brain and behavior · 2025Article
- Review
- Parent and child physical activity as possible predictors of quality of life in pediatric brain tumor patients: a dyadic analysis.Health psychology and behavioral medicine · 2025Article
- XAI-BT-EdgeNet: explainable edge-aware deep learning with squeeze-and-excitation for brain tumor detection and prediction.Frontiers in artificial intelligence · 2025Article
- Strategy-based cognitive rehabilitation for childhood brain tumour: Protocol for an acceptability and feasibility trial of the Fatigue, Learning, and Memory Enrichment (FLaME) intervention.NIHR open research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central nervous system (CNS) neoplasms are the most common solid tumors diagnosed in children. CNS tumors represent the leading cause of cancer death and cancer-related morbidity for children less than 20 years of age, although there has been a moderate increase in survival rates over the past several decades. The average survival at 5 years now nearly reaches 75%, and for some, non-malignant histology approximates 97% at 20 years from diagnosis. Neurological, cognitive, and neuropsychological deficits are the most disabling long-term effects of brain tumors in children. Childhood is a time of extreme brain sensitivity and the time of life in which most brain development occurs. Thus, the long-term toxicities that children treated for CNS tumors experience can affect multiple developmental domains and day-to-day functioning, ultimately leading to a poor quality of survival (QoS). We reviewed literature focusing on the risk factors for cognitive and neuropsychological impairment in pediatric patients treated for brain tumors with the aim of better understanding who is at major risk and what the best strategies for monitoring these patients are.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.