Evidence map›Paper›PMID 36979959›Full record

ArticleBiomedicines2023

The Role of the Left Inferior Parietal Cortex in Gilles de la Tourette Syndrome-An rTMS Study.

Theresa Paulus, Lynn Wernecke, Annik Lundie, Julia Friedrich, Julius Verrel, Tina Rawish, Anne Weissbach, Christian Frings, Christian Beste, Tobias Bäumer and 1 more

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Theresa PaulusInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Lynn WerneckeInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Annik LundieInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Julia FriedrichInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Julius VerrelInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Tina RawishInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Anne WeissbachInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.ORCID 0000-0002-3569-6242
Christian FringsDepartment of Cognitive Psychology, Faculty of Psychology, University of Trier, 54296 Trier, Germany.
Christian BesteCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden, 01307 Dresden, Germany.
Tobias BäumerInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Alexander MünchauInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
University of Lübeck · DEShandong Normal University · CNUniversität Trier · DE

Funding

Deutsche Forschungsgemeinschaft DFG, FOR 2698
6 · The paper itself

Abstract

Increased activity in the left inferior parietal cortex (BA40) plays a role in the generation of tics in the Gilles de la Tourette syndrome (GTS). Thus, inhibitory repetitive transcranial magnetic stimulation (rTMS) applied to BA40 was hypothesized to alleviate symptoms in GTS. We investigated the immediate effects of single-session 1 Hz rTMS and sham stimulation delivered to the left BA40 on tics assessed with the Rush video protocol in 29 adults with GTS. There were no significant effects on tic symptoms following rTMS or sham stimulation. Moreover, there was no difference when comparing the effects of both stimulation conditions. Bayesian statistics indicated substantial evidence against an intervention effect. The left BA40 appears not to be a useful target for 1 Hz rTMS to modulate tic symptoms in GTS patients.

Indexed as

BA40Gilles de la Tourette syndromeleft inferior parietal cortexrepetitive transcranial magnetic stimulationrush scoretics

Identifiers

PMID36979959
PMCPMC10046361
OpenAlexW4353061734

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read6
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.