Evidence map›Paper›PMID 36979870›Full record

ArticleBiomedicines2023

An Individualized Low-Pneumoperitoneum-Pressure Strategy May Prevent a Reduction in Liver Perfusion during Colorectal Laparoscopic Surgery.

Luis Enrique Olmedilla Arnal, Oscar Diaz Cambronero, Guido Mazzinari, José María Pérez Peña, Jaime Zorrilla Ortúzar, Marcos Rodríguez Martín, Maria Vila Montañes, Marcus J Schultz, Lucas Rovira, Maria Pilar Argente Navarro and 1 more

Open access · goldFull text read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Luis Enrique Olmedilla ArnalDepartment of Anaesthesiology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Oscar Diaz CambroneroPerioperative Medicine Research Group, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
Guido MazzinariPerioperative Medicine Research Group, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.ORCID 0000-0001-7377-331X
José María Pérez PeñaDepartment of Anaesthesiology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Jaime Zorrilla OrtúzarDepartment of Anaesthesiology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0003-1571-4586
Marcos Rodríguez MartínDepartment of Digestive Surgery, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Maria Vila MontañesPerioperative Medicine Research Group, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
Marcus J SchultzDepartment of Intensive Care, Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Amsterdam University Medical Centers, Location 'AMC', 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-3969-7792
Lucas RoviraDepartment of Anaesthesiology, Consorcio Hospital General Universitario de Valencia, 46014 Valencia, Spain.ORCID 0000-0002-3775-8144
Maria Pilar Argente NavarroPerioperative Medicine Research Group, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
On Behalf Of The IPPColLapSe Ii Investigators
Hospital General Universitario Gregorio Marañón · ESHospital Universitari i Politècnic La Fe · ESHospital General Universitario De Valencia · ESMahidol University · THUniversitat de València · ES

Funding

MSD (Spain) #53607
6 · The paper itself

Abstract

High intra-abdominal pressure (IAP) during laparoscopic surgery is associated with reduced splanchnic blood flow. It is uncertain whether a low IAP prevents this reduction. We assessed the effect of an individualized low-pneumoperitoneum-pressure strategy on liver perfusion. This was a single-center substudy of the multicenter 'Individualized Pneumoperitoneum Pressure in Colorectal Laparoscopic Surgery versus Standard Therapy II study' (IPPCollapse-II), a randomized clinical trial in which patients received an individualized low-pneumoperitoneum strategy (IPP) or a standard pneumoperitoneum strategy (SPP). Liver perfusion was indirectly assessed by the indocyanine green plasma disappearance rate (ICG-PDR) and the secondary endpoint was ICG retention rate after 15 min (R

Indexed as

colorectal surgerylaparoscopic colorectal surgerylaparoscopylow-impact laparoscopyperioperative medicinepneumoperitoneum

Identifiers

PMID36979870
PMCPMC10045598
OpenAlexW4324141593

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read7
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.