Evidence map›Paper›PMID 36979735›Full record

ReviewBiomedicines2023

Vascular Function in Continuous Flow LVADs: Implications for Clinical Practice.

Fouad Khalil, Rabea Asleh, Radha Kanneganti Perue, Jean-Marc Weinstein, Adam Solomon, Batya Betesh-Abay, Alexandros Briasoulis, Hilmi Alnsasra

Full text readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Physiologic effects of different hemodynamic patterns of LVAD.Frontiers in cardiovascular medicine · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fouad KhalilDepartment of Internal Medicine, University of South Dakota, Sioux Falls, SD 57105, USA.
Rabea AslehHeart Institute, Hadassah University Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem P.O. Box 12000, Israel.ORCID 0000-0002-0258-7402
Radha Kanneganti PerueDepartment of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0003-3792-6723
Jean-Marc WeinsteinFaculty of Health Sciences, Ben Gurion University of the Negev, Beersheva P.O. Box 653, Israel.
Adam SolomonFaculty of Health Sciences, Ben Gurion University of the Negev, Beersheva P.O. Box 653, Israel.
Batya Betesh-AbayFaculty of Health Sciences, Ben Gurion University of the Negev, Beersheva P.O. Box 653, Israel.ORCID 0000-0001-6672-443X
Alexandros BriasoulisDepartment of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.ORCID 0000-0002-5740-9670
Hilmi AlnsasraDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55902, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular assist devices (LVADs) have been increasingly used in patients with advanced heart failure, either as a destination therapy or as a bridge to heart transplant. Continuous flow (CF) LVADs have revolutionized advanced heart failure treatment. However, significant vascular pathology and complications have been linked to their use. While the newer CF-LVAD generations have led to a reduction in some vascular complications such as stroke, no major improvement was noticed in the rate of other vascular complications such as gastrointestinal bleeding. This review attempts to provide a comprehensive summary of the effects of CF-LVAD on vasculature, including pathophysiology, clinical implications, and future directions.

Indexed as

continuous flow left ventricular assist devicecoronary artery diseasegastrointestinal bleedingperipheral artery diseasepulmonary hypertensionstroke

Identifiers

PMID36979735
PMCPMC10045906

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.