Evidence map›Paper›PMID 36979680›Full record

ArticleBiomedicines2023

Evaluation of Four Rapid Antigen Tests for the Detection of SARS-CoV-2 Infection with Nasopharyngeal Swabs.

Ho-Jae Lim, Min-Young Park, Young-Hyun Baek, Hyeon-Seo Lee, Inhee Kim, Youngjin Kwon, Youngshin You, Kyoungwoo Nam, Jae-Hyun Yang, Min-Jin Kim and 4 more

Full text read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ho-Jae LimDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.ORCID 0000-0003-0115-5170
Min-Young ParkDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Young-Hyun BaekDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.ORCID 0000-0002-6894-9293
Hyeon-Seo LeeDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.ORCID 0000-0001-6358-5569
Inhee KimDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Youngjin KwonDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Youngshin YouDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Kyoungwoo NamDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.ORCID 0000-0003-2668-5207
Jae-Hyun YangPaul F. Glenn Center for Biology of Aging Research, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Min-Jin KimDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Nae YuDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Yong-Hak SohnDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.
Jung-Eun ParkDepartment of Integrative Biological Sciences & BK21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju 61452, Republic of Korea.ORCID 0000-0001-8789-9829
Yong-Jin YangDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Republic of Korea.ORCID 0000-0002-6153-9646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, the capacity of testing systems based on the gold standard real-time reverse transcription-polymerase chain reaction (rRT-PCR) is limited. Rapid antigen tests (RATs) can substantially contribute to the prevention of community transmission, but their further assessment is required. Here, using 1503 nasopharyngeal swabs, we compared the diagnostic performance of four RAT kits (Abbott Panbio™ COVID-19 Ag Rapid Test, SD Biosensor Standard™ Q COVID-19 Ag Test, Humasis COVID-19 Ag Test, and SG Medical Acrosis COVID-19 Ag Test) to the cycle threshold (Ct) values obtained from rRT-PCR. The precision values, area under the curve values, SARS-CoV-2 variant detection ability, and non-SARS-CoV-2 specificity of all four kits were similar. An assay using the Acrosis kit had a significantly better positive detection rate with a higher recall value and cut-off value than that using the other three RAT kits. During the current COVID-19 pandemic, the Acrosis kit is an effective tool to prevent the spread of SARS-CoV-2 in communities.

Indexed as

cut offrapid antigen testrRT-PCRSARS-CoV-2

Identifiers

PMID36979680
PMCPMC10045780

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.