Evidence map›Paper›PMID 36979642›Full record

ArticleBiomedicines2023

Effect of Quercetin Nanoparticles on Hepatic and Intestinal Enzymes and Stress-Related Genes in Nile Tilapia Fish Exposed to Silver Nanoparticles.

Mayada R Farag, Haitham G Abo-Al-Ela, Mahmoud Alagawany, Mahmoud M Azzam, Mohamed T El-Saadony, Stefano Rea, Alessandro Di Cerbo, Doaa S Nouh

Open access · goldFull text read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Rainbow Trout (International journal of molecular sciences · 2025
    Article
  3. Blood Biochemical Biomarkers in Fish Toxicology-A Review.Animals : an open access journal from MDPI · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Mayada R FaragForensic Medicine and Toxicology Department, Veterinary Medicine Faculty, Zagazig University, Zagazig 44519, Egypt.
Haitham G Abo-Al-ElaGenetics and Biotechnology, Department of Aquaculture, Faculty of Fish Resources, Suez University, Suez 43518, Egypt.ORCID 0000-0003-4157-5372
Mahmoud AlagawanyPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-8020-0971
Mahmoud M AzzamDepartment of Animal Production College of Food & Agriculture Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-9736-5468
Mohamed T El-SaadonyDepartment of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0001-8633-1836
Stefano ReaSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, Italy.
Alessandro Di CerboSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, Italy.ORCID 0000-0001-8122-9170
Doaa S NouhAnatomy and Embryology Department, Veterinary Medicine Faculty, Zagazig University, Zagazig 44519, Egypt.
Zagazig University · EGUniversità di Camerino · ITKing Saud University · SASuez University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, nanotechnology has become an important research field involved in the improvement of animals' productivity, including aquaculture. In this field, silver nanoparticles (AgNPs) have gained interest as antibacterial, antiviral, and antifungal agents. On the other hand, their extensive use in other fields increased natural water pollution causing hazardous effects on aquatic organisms. Quercetin is a natural polyphenolic compound of many plants and vegetables, and it acts as a potent antioxidant and therapeutic agent in biological systems. The current study investigated the potential mitigative effect of quercetin nanoparticles (QNPs) against AgNPs-induced toxicity in Nile tilapia via investigating liver function markers, hepatic antioxidant status, apoptosis, and bioaccumulation of silver residues in hepatic tissue in addition to the whole-body chemical composition, hormonal assay, intestinal enzymes activity, and gut microbiota. Fish were grouped into: control fish, fish exposed to 1.98 mg L

Indexed as

antioxidant capacityintestinal bacteriaNile tilapiaoxidative stressquercetinsilver nanoparticles

Identifiers

PMID36979642
PMCPMC10045288
OpenAlexW4321597300

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read4
measurements read53
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.