Evidence map›Paper›PMID 36979638›Full record

ArticleBiomedicines2023

Myositis-Specific and Myositis-Associated Antibodies in Fibromyalgia Patients: A Prospective Study.

Gianluca Sambataro, Martina Orlandi, Evelina Fagone, Mary Fruciano, Elisa Gili, Alessandro Libra, Stefano Palmucci, Carlo Vancheri, Lorenzo Malatino, Michele Colaci and 1 more

Open access · goldFull text read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gianluca SambataroArtroreuma s.r.l., Rheumatology Outpatient Clinic, 95030 Mascalucia, CT, Italy.ORCID 0000-0001-9933-1202
Martina OrlandiDepartment of Experimental and Clinical Medicine, Division of Rheumatology AOUC Careggi, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-6784-2235
Evelina FagoneDepartment of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Disease, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Mary FrucianoDepartment of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Disease, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Elisa GiliDepartment of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Disease, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Alessandro LibraDepartment of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Disease, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Stefano PalmucciDepartment of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University Hospital Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.ORCID 0000-0002-7196-2974
Carlo VancheriDepartment of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Disease, Policlinico "G. Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Lorenzo MalatinoInternal Medicine Unit, Department of Clinical and Experimental Medicine, Division of Rheumatology, Cannizzaro Hospital, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2944-2729
Michele ColaciInternal Medicine Unit, Department of Clinical and Experimental Medicine, Division of Rheumatology, Cannizzaro Hospital, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-3606-3404
Domenico SambataroArtroreuma s.r.l., Rheumatology Outpatient Clinic, 95030 Mascalucia, CT, Italy.
University of Catania · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibromyalgia (FM) is a common rheumatologic disorder characterised by widespread muscular pain. Myalgia is also a common clinical feature in Connective Tissue Disease (CTD), and FM should be studied for the concomitant presence of a CTD. The aim of this study is to evaluate the prevalence of Myositis-Specific and Myositis-Associated Antibodies (MSA/MAA) in a cohort of FM patients. We enrolled 233 consecutive FM patients (defined according to the 2016 criteria) that did not report clinical signs of autoimmune disorders and followed them for at least one year. The patients were tested for MSA/MAA with immunoblotting. FM patients were seropositive for Antinuclear Antibodies (ANA) in 24% of cases, for MSA in 9%, and for MAA in 6%. A specific diagnosis of CTD was made in 12 patients (5.2%), namely, 5 cases of primary Sjögren's Syndrome and 7 of Idiopathic Inflammatory Myopathy. Seropositive patients showed clinical features similar to those who were seronegative at baseline. A CTD diagnosis was associated with ANA positivity (

Indexed as

antisynthetase syndromedermatomyositisdiagnosisfibromyalgiaidiopathic inflammatory myopathymyalgiamyositis-associated antibodiesmyositis-specific antibodiespolymyositisSjögren’s syndrome

Identifiers

PMID36979638
PMCPMC10045737
OpenAlexW4321495557

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.