Evidence map›Paper›PMID 36979618›Full record

ArticleBiosensors2023

Clinically Deployable Bioelectronic Sensing Platform for Ultrasensitive Detection of Transferrin in Serum Sample.

Harleen Kaur, Prasanthi Chittineedi, Ravi Shankar Bellala, Venkata Madhavi Bellala, Sandeep Singh, Rohini Kumari, Pranjal Chandra, Santhi Latha Pandrangi, Surinder P Singh

Open access · goldFull text read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. An electrochemical aptasensor for detection ofFrontiers in bioengineering and biotechnology · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Harleen KaurCSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi 110012, India.
Prasanthi ChittineediOnco-Stem Cell Research Laboratory, Department of Biochemistry and Bioinformatics, GITAM School of Science, GITAM (Deemed to be) University, Visakhapatnam 530045, India.
Ravi Shankar BellalaDepartment of Clinical Oncology, Omega Hospitals, Visakhapatnam 530040, India.
Venkata Madhavi BellalaDepartment of Pathology, GITAM Institute of Medical Sciences and Research, Visakhapatnam 530045, India.
Sandeep SinghCSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi 110012, India.
Rohini KumariLaboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi 221005, India.
Pranjal ChandraLaboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi 221005, India.ORCID 0000-0003-3428-3195
Santhi Latha PandrangiOnco-Stem Cell Research Laboratory, Department of Biochemistry and Bioinformatics, GITAM School of Science, GITAM (Deemed to be) University, Visakhapatnam 530045, India.ORCID 0000-0001-5317-8716
Surinder P SinghCSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi 110012, India.
Council of Scientific and Industrial Research · INGITAM University · INIndian Institute of Technology BHU · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varying levels of transferrin (Tf) have been associated with different disease conditions and are known to play a crucial role in various malignancies. Regular monitoring of the variations in Tf levels can be useful for managing related diseases, especially for the prognosis of certain cancers. We fabricated an immunosensor based on graphene oxide (GO) nanosheets to indirectly detect Tf levels in cancer patients. The GO nanosheets were deposited onto an indium tin oxide (ITO)-coated glass substrate and annealed at 120 °C to obtain reduced GO (rGO) films, followed by the immobilization of an antibody, anti-Tf. The materials and sensor probe used were systematically characterized by UV-Visible spectroscopy (UV-Vis), X-ray diffraction (XRD), atomic force microscopy (AFM), and Fourier transform infrared spectroscopy (FTIR). Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV) were also used for the stepwise sensor probe characterizations and Tf detection in serum samples, respectively. The anti-Tf/rGO/ITO immunosensor DPV output demonstrated an excellent Tf detection capability in the linear range of 0.1 mg mL

Indexed as

Biosensing TechniquesGraphiteNeoplasmsElectrochemical TechniquesHumansImmunoassayLimit of DetectionTin CompoundsTransferringraphene oxideGraphiteindium tin oxideTin CompoundsTransferrinelectrochemical detectionferritinimmunosensorsreduced graphene oxidetransferrin

Identifiers

PMID36979618
PMCPMC10046405
OpenAlexW4328123477

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read57
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.