Evidence map›Paper›PMID 36979593›Full record

ArticleBiosensors2023

Serum Autoantibody Biomarkers for Management of Rheumatoid Arthritis Disease.

Esther Sánchez-Tirado, Lourdes Agüí, Marta Sánchez-Paniagua, Araceli González-Cortés, Beatriz López-Ruiz, Paloma Yáñez-Sedeño, José M Pingarrón

Open access · goldFull text read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Neutrophil extracellular traps in homeostasis and disease.Signal transduction and targeted therapy · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Esther Sánchez-TiradoDepartment of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2386-4552
Lourdes AgüíDepartment of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6307-7943
Marta Sánchez-PaniaguaDepartment of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, University Complutense of Madrid, 28040 Madrid, Spain.
Araceli González-CortésDepartment of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-9054-9993
Beatriz López-RuizDepartment of Chemistry in Pharmaceutical Sciences, Faculty of Pharmacy, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5425-8953
Paloma Yáñez-SedeñoDepartment of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1232-2723
José M PingarrónDepartment of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2271-1383
Universidad Complutense de Madrid · ES

Funding

Comunidad de Madrid S2018/NMT-4349Spanish Ministerio de Ciencia e Innovación PID2021-122457OB-I00
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a systemic chronic autoimmune inflammatory disease that is characterized by the destruction of bone and production of autoantibodies such as rheumatoid factor (RF) and anticitrullinated protein antibodies (ACPAs). The high prevalence of this disease and the need of affordable tools for its early detection led us to prepare the first electrochemical immunoplatform for the simultaneous determination of four RA biomarkers, the autoantibodies: RF, anti-peptidyl-arginine deiminase enzyme (anti-PAD4), anti-cyclic citrullinated peptide (anti-CCP), and anti-citrullinated vimentin (anti-MCV). Functionalized magnetic beads (MBs) were used to immobilize the specific antigens, and sandwich-type immunoassays were implemented for the amperometric detection of the four autoantibodies, using the horseradish peroxidase (HRP)/H

Indexed as

Arthritis, RheumatoidAutoantibodiesBiomarkersEnzyme-Linked Immunosorbent AssayHumansHydrogen PeroxideAutoantibodiesBiomarkersHydrogen Peroxideautoantibodieselectrochemical platformimmunosensingmagnetic microbeadsmultiplexrheumatoid arthritis

Identifiers

PMID36979593
PMCPMC10046368
OpenAlexW4324150336

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read20
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.