Evidence map›Paper›PMID 36979551›Full record

ArticleBiosensors2023

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype.

Daan C 't Hart, Dilemin Yildiz, Valentina Palacio-Castañeda, Lanhui Li, Burcu Gumuscu, Roland Brock, Wouter P R Verdurmen, Johan van der Vlag, Tom Nijenhuis

Open access · goldFull text read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Daan C 't HartDepartment of Nephrology, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0003-2718-9432
Dilemin YildizDepartment of Nephrology, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0002-3176-5159
Valentina Palacio-CastañedaDepartment of Medical Biosciences, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0001-9314-4000
Lanhui LiBiosensors and Devices Laboratory, Biomedical Engineering Department, Institute for Complex Molecular Systems, Eindhoven Artificial Intelligence Systems Institute, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Burcu GumuscuBiosensors and Devices Laboratory, Biomedical Engineering Department, Institute for Complex Molecular Systems, Eindhoven Artificial Intelligence Systems Institute, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.ORCID 0000-0003-4843-4724
Roland BrockDepartment of Medical Biosciences, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Wouter P R VerdurmenDepartment of Medical Biosciences, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0002-2463-277X
Johan van der VlagDepartment of Nephrology, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Tom NijenhuisDepartment of Nephrology, Research Institute for Medical Innovations, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0002-4375-7236
Radboud University Nijmegen · NLEindhoven University of Technology · NL

Funding

Nierstichting 13OKS023Nierstichting 19PhD23
6 · The paper itself

Abstract

Crosstalk between glomerular endothelial cells and glomerular epithelial cells (podocytes) is increasingly becoming apparent as a crucial mechanism to maintain the integrity of the glomerular filtration barrier. However,

Indexed as

PodocytesCoculture TechniquesEndothelial CellsLab-On-A-Chip DevicesRNARNAbiological barrierco-culturecrosstalkglomerular endothelial cellsglomerular filtration barrierglomerulusglomerulus-on-a-chiporgan-on-a-chippodocytes

Identifiers

PMID36979551
PMCPMC10046631
OpenAlexW4323314286

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.