Evidence map›Paper›PMID 36979531›Full record

ReviewBiosensors2023

Intravascular Imaging of Atherosclerosis by Using Engineered Nanoparticles.

Jiawen Li, Franco Centurion, Rouyan Chen, Zi Gu

Open access · goldFull text readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Identification and validation of mitochondrial endoplasmic reticulum membrane-related genes in atherosclerosis.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  5. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jiawen LiSchool of Electrical and Mechanical Engineering, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0001-8818-6070
Franco CenturionSchool of Chemical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-7961-3293
Rouyan ChenSchool of Electrical and Mechanical Engineering, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-7323-8699
Zi GuSchool of Chemical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-7153-6596
UNSW Sydney · AUAustralian Research Council · AUThe University of Adelaide · AU

Funding

Australian Research Council DP200103587National Health and Medical Research Council 2001646National Health and Medical Research Council 2008462NSW Cardiovascular Research Capacity Program Early-Mid Career Researcher Grant NAUNSW-CAS Collaboration Seed Grant NAUNSW RNA Institute Seed Grant NAWellcome Trust 105608
6 · The paper itself

Abstract

Atherosclerosis is a leading cause of morbidity and mortality, and high-risk atherosclerotic plaques can result in myocardial infarction, stroke, and/or sudden death. Various imaging and sensing techniques (e.g., ultrasound, optical coherence tomography, fluorescence, photoacoustic) have been developed for scanning inside blood vessels to provide accurate detection of high-risk atherosclerotic plaques. Nanoparticles have been utilized in intravascular imaging to enable targeted detection of high-risk plaques, to enhance image contrast, and in some applications to also provide therapeutic functions of atherosclerosis. In this paper, we review the recent progress on developing nanoparticles for intravascular imaging of atherosclerosis. We discuss the basic nanoparticle design principles, imaging modalities and instrumentations, and common targets for atherosclerosis. The review is concluded and highlighted with discussions on challenges and opportunities for bringing nanoparticles into in vivo (pre)clinical intravascular applications.

Indexed as

AtherosclerosisNanoparticlesPlaque, AtheroscleroticHumansSpectrum AnalysisTomography, Optical Coherenceatherosclerosisengineered nanoparticlesfluorescenceintravascular imagingphotoacoustic imaging

Identifiers

PMID36979531
PMCPMC10046792
OpenAlexW4322502095

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read9
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.