Evidence map›Paper›PMID 36979510›Full record

ArticleBiomolecules2023

Purification and Biological Properties of Raniseptins-3 and -6, Two Antimicrobial Peptides from

Gabriel Gonçalves de Freitas, João Martins Barbosa, Carlos José Correia de Santana, Ana Carolina Martins Magalhães, Keven Wender Rodrigues Macedo, Jéssica Oliveira de Souza, Jessica Schneider de Castro, Isadora Alves de Vasconcelos, Amanda Araújo Souza, Sonia Maria de Freitas and 8 more

Full text read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Gabriel Gonçalves de FreitasLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-0976-6921
João Martins BarbosaLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.
Carlos José Correia de SantanaLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0001-9781-3670
Ana Carolina Martins MagalhãesLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0003-1776-2426
Keven Wender Rodrigues MacedoLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0003-3758-5615
Jéssica Oliveira de SouzaLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.
Jessica Schneider de CastroLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-8271-1783
Isadora Alves de VasconcelosLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0001-8091-3712
Amanda Araújo SouzaBrazilian Biosciences National Laboratory (LNBio), National Center for Research in Energy and Materials (CNPEM), Campinas 13083-970, SP, Brazil.
Sonia Maria de FreitasLaboratory of Biophysics, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-7562-4980
Sônia Nair BáoElectron Microscopy Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-9873-3098
Samuel Ribeiro CostaLaboratory of Synthesis and Analysis of Biomolecules, Institute of Chemistry, University of Brasilia, Brasilia 70.910-900, DF, Brazil.
Guilherme Dotto BrandLaboratory of Synthesis and Analysis of Biomolecules, Institute of Chemistry, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-1615-0009
Ian de Meira ChavesCenter for Research and Development of Pharmaceuticals, Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
Vivian Vasconcelos CostaCenter for Research and Development of Pharmaceuticals, Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
Wagner FontesLaboratory of Protein Chemistry and Biochemistry, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0001-5140-8573
Osmindo Rodrigues Pires JúniorLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0002-9875-9407
Mariana S CastroLaboratory of Toxinology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasilia, Brasilia 70.910-900, DF, Brazil.ORCID 0000-0001-5143-152X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of multidrug-resistant pathogenic microorganisms has been growing in recent years, most of which is due to the inappropriate use of the commercial antibiotics that are currently available. The dissemination of antimicrobial resistance represents a serious global public health problem. Thus, it is necessary to search for and develop new drugs that can act as antimicrobial agents. Antimicrobial peptides are a promising alternative for the development of new therapeutic drugs. Anurans' skin glands are a rich source of broad-spectrum antimicrobial compounds and hylids, a large and diverse family of tree frogs, are known as an important source of antimicrobial peptides. In the present study, two novel antimicrobial peptides, named Raniseptins-3 and -6, were isolated from

Indexed as

Anti-Infective AgentsAntimicrobial Cationic PeptidesAnimalsAnti-Bacterial AgentsAntimicrobial PeptidesAnuraMiceMicrobial Sensitivity TestsNIH 3T3 CellsSkinAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesAntimicrobial Peptidesantimicrobial peptidesanuransBoana ranicepsRaniseptinsskin secretion

Identifiers

PMID36979510
PMCPMC10046390

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LicenceCC BY
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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.