ReviewBiomolecules2023
Glaucoma and Myopia: Diagnostic Challenges.
Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- National, regional, and provincial prevalence of glaucoma in China in 2020: an updated systematic review and modelling analysis.Journal of global health · 2025Pooled it
- Comprehensive assessment of glaucoma in patients with high myopia: a systematic review and meta-analysis with a discussion of structural and functional imaging modalities.International ophthalmology · 2024Pooled it
- Computational study of DurystaDrug delivery and translational research · 2026Article
- Adipose-Derived Mesenchymal Stem Cell Exosome miR-146a-5p Attenuates TGF-β2-Induced Transformation of Human Tenon's Capsule Fibroblasts by Targeting SMAD4.Investigative ophthalmology & visual science · 2026Article
- Deep Learning and Radiomics Assessment for Highly Myopic Glaucoma Detection Based on Fundus Photography.Ophthalmology science · 2026Article
- Stereophotographic Assessment of Intraocular Pressure Reduction in Myopic Eyes with Glaucoma-Compatible Optic Neuropathy.Ophthalmology and therapy · 2026Article
- Myopic and Glaucomatous Optic Neuropathy in Highly Myopic Eyes: A Practical Framework for Diagnosis, Monitoring, and Management.Journal of clinical medicine · 2026Review
- GCIPL color coding on OCT predicts glaucoma conversion in normal-tension glaucoma suspects, including a high myopia subgroup.Scientific reports · 2026Article
- Corneal morphological changes after discontinuation of long-term orthokeratology and SMILE surgery outcomes: a retrospective comparative study.BMC ophthalmology · 2026Article
- Interaction of Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Pathophysiology and Clinical Implications.Journal of clinical medicine · 2026Review
- Evaluating multimodal large language models for differential diagnosis of high myopia versus high myopia with Glaucoma.Frontiers in medicine · 2026Article
- Lifestyle behaviors, serum metabolites and high myopia: Mendelian randomization and mediation analysis.International journal of ophthalmology · 2026Article
- Comparison of correction formulas for intraocular pressure measured by Goldmann tonometer following various refractive surgeries (FS-LASIK, SMILE, tPRK).Frontiers in bioengineering and biotechnology · 2026Article
- Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes.International journal of ophthalmology · 2026Article
- Differences of the lamina cribrosa between primary open angle glaucoma and non-pathologic high myopia.International journal of ophthalmology · 2026Review
- Selective retinal neuron loss and impaired neurovascular support underlie myopic retinopathy in RPE-specific Lrp2-deficient mice.Frontiers in cellular neuroscience · 2026Article
- Risk Factors for Visual Field Progression in Primary Angle Closure Disease Over 10 Years: The CUPAL Study.Investigative ophthalmology & visual science · 2025Article
- A deep learning model integrating domain-specific features for enhanced glaucoma diagnosis.BMC medical informatics and decision making · 2025Article
- Diagnosis of early glaucoma likely combined with high myopia by integrating OCT thickness map and standard automated and Pulsar perimetries.Scientific reports · 2025Article
- Global trends and hotspots in artificial intelligence for high myopia: a bibliometric analysis.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The rising global prevalence of myopia is a growing concern for clinicians, as it predisposes patients to severe ocular pathologies including glaucoma. High myopia can be associated with clinical features that resemble glaucomatous damage, which make an accurate glaucoma diagnosis challenging, particularly among patients with normal intraocular pressures. These patients may also present with established visual field defects which can mimic glaucoma, and standard imaging technology is less useful in disease detection and monitoring due to the lack of normative data for these anatomically unique eyes. Progression over time remains the most critical factor in facilitating the detection of early glaucomatous changes, and thus careful longitudinal follow-up of high-risk myopic patients is the most important aspect of management. Here, we review our current understanding of the complex relationship between myopia and glaucoma, and the diagnostic challenges and limitations of current testing protocols including visual field, intraocular pressure, and imaging. Furthermore, we discuss the clinical findings of two highly myopic patients with suspected glaucoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.