Evidence map›Paper›PMID 36979429›Full record

ReviewBiomolecules2023

Applications of Genomics and Transcriptomics in Precision Medicine for Myopia Control or Prevention.

Liqin Jiang, Dong Xuan Goh, James Hao Zhong Koh, Xavier Chan, Noel A Brennan, Veluchamy Amutha Barathi, Quan V Hoang

Open access · goldFull text readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Antifungal Mechanism of Phenazine-1-Carboxylic Acid againstInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Liqin JiangSingapore Eye Research Institute, Singapore National Eye Centre, Eye ACP Duke-NUS Medical School, Singapore 169856, Singapore.
Dong Xuan GohLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.
James Hao Zhong KohSingapore Eye Research Institute, Singapore National Eye Centre, Eye ACP Duke-NUS Medical School, Singapore 169856, Singapore.
Xavier ChanSingapore Eye Research Institute, Singapore National Eye Centre, Eye ACP Duke-NUS Medical School, Singapore 169856, Singapore.ORCID 0000-0002-5946-0322
Noel A BrennanJohnson & Johnson Vision, Jacksonville, FL 32256, USA.
Veluchamy Amutha BarathiSingapore Eye Research Institute, Singapore National Eye Centre, Eye ACP Duke-NUS Medical School, Singapore 169856, Singapore.ORCID 0000-0002-6477-9784
Quan V HoangSingapore Eye Research Institute, Singapore National Eye Centre, Eye ACP Duke-NUS Medical School, Singapore 169856, Singapore.ORCID 0000-0002-5486-9292
Singapore National Eye Center · SGNational University of Singapore · SGJohnson & Johnson (United States) · USNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myopia is a globally emerging concern accompanied by multiple medical and socio-economic burdens with no well-established causal treatment to control thus far. The study of the genomics and transcriptomics of myopia treatment is crucial to delineate disease pathways and provide valuable insights for the design of precise and effective therapeutics. A strong understanding of altered biochemical pathways and underlying pathogenesis leading to myopia may facilitate early diagnosis and treatment of myopia, ultimately leading to the development of more effective preventive and therapeutic measures. In this review, we summarize current data about the genomics and transcriptomics of myopia in human and animal models. We also discuss the potential applicability of these findings to precision medicine for myopia treatment.

Indexed as

MyopiaPrecision MedicineAnimalsGene Expression ProfilingGenomicsHumansTranscriptomeanimal modelsgenomicsGWASmolecularMyopiatranscriptomics

Identifiers

PMID36979429
PMCPMC10046175
OpenAlexW4323565289

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read7
reference markers read13
identifiers read13
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.