Evidence map›Paper›PMID 36979428›Full record

ReviewBiomolecules2023

The Impact of Flavonoid-Loaded Nanoparticles in the UV Protection and Safety Profile of Topical Sunscreens.

Magda Fonseca, Mubashar Rehman, Raquel Soares, Pedro Fonte

Open access · goldFull text readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Dermocosmetic Potential ofAntioxidants (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Prunin: An Emerging Anticancer Flavonoid.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Magda FonsecaEPI Unit, Department of Epidemiological Research, Institute of Public Health of University of Porto (ISPUP), Rua das Taipas 135, 4050-600 Porto, Portugal.
Mubashar RehmanDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.ORCID 0000-0002-7605-8861
Raquel SoaresDepartment of Biomedicine, Faculty of Medicine, University of Porto, Al Prof Hernani Monteiro, 4200-319 Porto, Portugal.ORCID 0000-0002-9157-5541
Pedro FonteCenter for Marine Sciences (CCMAR), Gambelas Campus, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-1115-9282
Universidade do Porto · PTQuaid-i-Azam University · PKUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive UV radiation exposure is harmful to skin cells since sunburn is accompanied by oxidative burst, leading to a rapid increase in skin cancer. However, the insufficient UV photoprotection of approved sunscreens and the negative impact of their compositions on ecosystems and human health makes the utility of sunscreen a questionable recommendation. Therefore, discovering UV filters with significant antioxidant activity and improved topical performance and photostability is an urgent need. Recently, the use of nanosized natural molecules incorporated in sunscreens has been a scientific hot topic, as it has been suggested that they provide a synergistic effect with synthetic UV filters, improving overall SPF and antioxidant activity, higher retention on the epidermis, and less toxicity. The aim of this review was to verify the usefulness of sunscreens incorporating flavonoid-loaded nanoparticles. A literature review was performed, where original and review articles published in the last 6 years were analyzed. Formulations containing nanosized flavonoids with improved UVA photoprotection and safer toxicological profiles, associated or not with synthetic filters, are promising sunscreens and more clinical investigation must be performed to validate these findings.

Indexed as

Sunscreening AgentsUltraviolet RaysAntioxidantsEcosystemFlavonoidsHumansSkinAntioxidantsFlavonoidsSunscreening Agentsantioxidantflavonoidnanoparticleskin cancersunscreenUVA photoprotectionUV filter

Identifiers

PMID36979428
PMCPMC10046639
OpenAlexW4323565255

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read81
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.