ReviewBiomolecules2023
Surface Treatments of PEEK for Osseointegration to Bone.
Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Soft, Reactive, and Alive: A Dynamic Framework for Degradation and Functional Stability of Polymeric Biomaterials.Polymers · 2026Review
- Photocontrolled biomimetic PEEK scaffold with black phosphorus-strontium ion cascade release for vascularized bone regeneration.Materials today. Bio · 2026Article
- An Ion-Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR-Mediated Antibacterial Activity of PEEK.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- PEEK in modern maxillofacial surgery: clinical applications, limitations and future opportunities.British dental journal · 2026Review
- Dual reinforcement of PEKK composites with hydroxyapatite and silicon nitride nanowires for enhanced mechanical, tribological, antibacterial, and osteogenic performance.Journal of nanobiotechnology · 2026Article
- Application-matched point-of-care 3D printing of functionalized polyetheretherketone (PEEK) composites for patient-specific craniomaxillofacial implants.3D printing in medicine · 2026Article
- From Concept to Clinic: Pre-Clinical Testing and Regulatory Considerations in Spine Implant Development.JOR spine · 2026Review
- Amination-degradation of super engineering plastics for the construction of surface emissive resin materials.Communications chemistry · 2026Article
- Polyetheretherketone (PEEK) in maxillofacial reconstruction surgery: a narrative review.Annals of medicine and surgery (2012) · 2026Review
- Role of polyetheretherketone (PEEK) in arthroplasty and orthopaedics: a review of biomechanical properties, surface modifications, and clinical outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Review
- Surface Modification of Polyetheretherketone (PEEK) via Femtosecond Laser Microprocessing for Enhanced Bioactivity: A Preliminary Study.Bioengineering (Basel, Switzerland) · 2025Article
- Biofunctionalization of 3D printed PEEK using integrated cathodic arc plasma coating: a one-step solution to antimicrobial and bioactive PEEK Implant.Journal of materials science. Materials in medicine · 2025Article
- Polyetheretherketone for craniomaxillofacial defects: cases report, evaluation of patients' satisfaction and a systematic literature review.Maxillofacial plastic and reconstructive surgery · 2025Article
- Cutting Edge Era of Additively Manufactured Patient Specific Titanium Implants for Expeditious Extensive Cranioplasties.Journal of maxillofacial and oral surgery · 2025Article
- Effects of surface treatments on the adhesion strengths between polyether ether ketone and both composite resins and poly(methyl methacrylate).BMC oral health · 2025Article
- Sulfonated polyether ketone ketone (SPEKK) implant as an alternative to titanium implant-in vivo study on Wistar Albino rat mandible.BMC oral health · 2025Article
- A Comparative Finite Element Analysis of Titanium, Autogenous Bone, and Polyetheretherketone (PEEK)-Based Solutions for Mandibular Reconstruction.Materials (Basel, Switzerland) · 2025Article
- 3D-printed PEEK versus conventional free fibula flap for jaw reconstruction: a comparative clinical study.Frontiers in oncology · 2025Article
- Revolutionizing Dental Polymers: The Versatility and Future Potential of Polyetheretherketone in Restorative Dentistry.Polymers · 2024Review
- Cranial reconstruction utilizing polymeric implants in two different designs: finite element investigation.BMC musculoskeletal disorders · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymers, in general, and Poly (Ether-Ether-Ketone) (PEEK) have emerged as potential alternatives to conventional osseous implant biomaterials. Due to its distinct advantages over metallic implants, PEEK has been gaining increasing attention as a prime candidate for orthopaedic and dental implants. However, PEEK has a highly hydrophobic and bioinert surface that attenuates the differentiation and proliferation of osteoblasts and leads to implant failure. Several improvements have been made to the osseointegration potential of PEEK, which can be classified into three main categories: (1) surface functionalization with bioactive agents by physical or chemical means; (2) incorporation of bioactive materials either as surface coatings or as composites; and (3) construction of three-dimensionally porous structures on its surfaces. The physical treatments, such as plasma treatments of various elements, accelerated neutron beams, or conventional techniques like sandblasting and laser or ultraviolet radiation, change the micro-geometry of the implant surface. The chemical treatments change the surface composition of PEEK and should be titrated at the time of exposure. The implant surface can be incorporated with a bioactive material that should be selected following the desired use, loading condition, and antimicrobial load around the implant. For optimal results, a combination of the methods above is utilized to compensate for the limitations of individual methods. This review summarizes these methods and their combinations for optimizing the surface of PEEK for utilization as an implanted biomaterial.
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Registered trials
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