Evidence map›Paper›PMID 36979285›Full record

ArticleBrain sciences2023

Effects of Paired Associative Stimulation on Cortical Plasticity in Agonist-Antagonist Muscle Representations.

Makoto Suzuki, Kazuo Saito, Yusuke Maeda, Kilchoon Cho, Naoki Iso, Takuhiro Okabe, Takako Suzuki, Junichi Yamamoto

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Makoto SuzukiFaculty of Health Sciences, Tokyo Kasei University, 2-15-1 Inariyama, Sayama City 350-1398, Saitama, Japan.
Kazuo SaitoFaculty of Health Sciences, Tokyo Kasei University, 2-15-1 Inariyama, Sayama City 350-1398, Saitama, Japan.ORCID 0000-0001-7026-5395
Yusuke MaedaSchool of Health Sciences at Odawara, International University of Health and Welfare, 1-2-25 Shiroyama, Odawara City 250-8588, Kanagawa, Japan.
Kilchoon ChoFaculty of Health Sciences, Tokyo Kasei University, 2-15-1 Inariyama, Sayama City 350-1398, Saitama, Japan.
Naoki IsoFaculty of Health Sciences, Tokyo Kasei University, 2-15-1 Inariyama, Sayama City 350-1398, Saitama, Japan.
Takuhiro OkabeFaculty of Health Sciences, Tokyo Kasei University, 2-15-1 Inariyama, Sayama City 350-1398, Saitama, Japan.ORCID 0000-0003-3360-5068
Takako SuzukiSchool of Health Sciences, Saitama Prefectural University, 820 Sannomiya, Koshigaya City 343-8540, Saitama, Japan.
Junichi YamamotoFaculty of Systems Design, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji City 192-0397, Tokyo, Japan.
Tokyo Kasei University · JPInternational University of Health and Welfare · JPSaitama Prefectural University · JPTokyo Metropolitan University · JP

Funding

Japan Science and Technology Agency [Moonshot R&D] [Grant Number JPMJMS2034-15]Japan Society for the Promotion of Science KAKENHI 18K19750
6 · The paper itself

Abstract

Paired associative stimulation (PAS) increases and decreases cortical excitability in primary motor cortex (M1) neurons, depending on the spike timing-dependent plasticity, i.e., long-term potentiation (LTP)- and long-term depression (LTD)-like plasticity, respectively. However, how PAS affects the cortical circuits for the agonist and antagonist muscles of M1 is unclear. Here, we investigated the changes in the LTP- and LTD-like plasticity for agonist and antagonist muscles during PAS: 200 pairs of 0.25-Hz peripheral electric stimulation of the right median nerve at the wrist, followed by a transcranial magnetic stimulation of the left M1 with an interstimulus interval of 25 ms (PAS-25 ms) and 10 ms (PAS-10 ms). The unconditioned motor evoked potential amplitudes of the agonist muscles were larger after PAS-25 ms than after PAS-10 ms, while those of the antagonist muscles were smaller after PAS-25 ms than after PAS-10 ms. The γ-aminobutyric acid A (GABA

Indexed as

agonist–antagonist musclehumanlong-term potentiationmagnetic stimulationpaired associative stimulation

Identifiers

PMID36979285
PMCPMC10046224
OpenAlexW4324058412

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LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.