ArticleBrain sciences2023
Association between Systemic Immune Inflammation Index and Cognitive Impairment after Acute Ischemic Stroke.
Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 14 citations in OpenAlex.
- Stage-specific utility of obesity indices across the chronic kidney disease continuum.Renal failure · 2026Article
- Mechanisms and biomarkers of poststroke cognitive impairment.Neural regeneration research · 2026Article
- Admission Systemic Immune-Inflammation Index Is Associated with Cognitive Performance and Handgrip Strength Three Months After First-Ever Acute Ischaemic Stroke: A Prospective Cohort Study.Brain sciences · 2026Article
- Systemic immune-inflammation index, stress hyperglycemia ratio and triglyceride-glucose index in acute ischemic stroke: an integrated inflammation-stress-metabolism perspective.Frontiers in neurology · 2026Review
- Advanced radiomics techniques applied on carotid duplex ultrasound data predict adverse outcomes in acute ischemic stroke.Frontiers in neurology · 2026Article
- Correlation Between Serum TGF-β1 Levels, Intracranial Atherosclerotic Plaque Parameters and Post-Stroke Cognitive Impairment.International journal of general medicine · 2026Article
- Determinants of Post-Stroke Cognitive Impairment After Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Neuropsychiatric disease and treatment · 2026Review
- Association between post-stroke cognitive impairment and gut microbiota in patients with ischemic stroke.Scientific reports · 2025Article
- Lack of correlation between cerebral arteriovenous malformation angioarchitectural and hemodynamic characteristics and systemic inflammation.Acta neurochirurgica · 2025Article
- Effect of Novel Inflammatory Biomarkers on Adverse Outcomes in Patients with Interstitial Lung Disease and Pneumonia: A Multicenter Retrospective Cohort Study.Combinatorial chemistry & high throughput screening · 2025Article
- Higher systemic immune-inflammation index is associated with increased risk of Parkinson's disease in adults: a nationwide population-based study.Frontiers in aging neuroscience · 2025Article
- Peripheral immunity is associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack.Scientific reports · 2024Article
- Association between systemic immune-inflammation index and post-stroke depression: a cross-sectional study of the national health and nutrition examination survey 2005-2020.Frontiers in neurology · 2024Article
- Association between systemic immune-inflammation index and chronic kidney disease: A population-based study.PloS one · 2024Article
- C-Reactive Protein Levels and Cognitive Decline following Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Brain sciences · 2023Review
- A COMPREHENSIVE EVALUATION OF HEMOGRAM-DERIVED INFLAMMATORY INDICES IN HASHIMOTO THYROIDITIS AND NON-IMMUNOGENIC HYPOTHYROIDISM.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsPost-stroke cognitive impairment (PSCI) is one of the major complications after ischemic stroke. PSCI has been shown to be associated with low-grade systemic inflammation. As a novel inflammatory marker, the systemic immune-inflammation (SII) index could reflect clinical outcomes in severe cardiovascular diseases. We therefore performed a prospective study to investigate the correlation between the SII index and the risk of PSCI in patients with ischemic stroke.
methodsWe prospectively enrolled 254 patients with ischemic stroke with symptoms onset <72 h. The SII index was detected within 24 h after admission. The Montreal Cognitive Scale (MoCA) was utilized to evaluate cognitive function, and PSCI was defined as a MoCA score of <25 points.
resultsDuring the 3-month follow-up, 70 participants (27.6%) had mild cognitive impairment and 60 (23.6%) had severe cognitive impairment. In binary logistic regression analysis, each one-standard deviation increase in the SII index was significantly associated with the prevalence of PSCI after adjusting for age, sex, and other confounders (odds ratio 2.341; 95% confidence interval, 1.439-3.809,
conclusionsOur study indicated that an increased SII index was closely related to PSCI at 3 months in patients with ischemic stroke. Further research is required to evaluate the efficacy of inflammation management in these patients.
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