Evidence map›Paper›PMID 36979216›Full record

ArticleBrain sciences2023

Executive Profile of the Logopenic Variant of Primary Progressive Aphasia: Comparison with the Semantic and Non-Fluent Variants and Alzheimer's Disease.

Sandrine Basaglia-Pappas, Bernard Laurent, Jean-Claude Getenet, Anne Boulangé, Aurelia Rendón de laCruz, Isabelle Simoes Loureiro, Laurent Lefebvre

Open access · goldFull text read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Theory of mind deficits in non-fluent primary progressive aphasia.Cortex; a journal devoted to the study of the nervous system and behavior · 2025
    Article
  6. Screening for Executive Impairment in Patients with Frontotemporal Dementia: Evidence from the Greek Version of the Frontier Executive Screen.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sandrine Basaglia-PappasDepartment of Neurology and Neuropsychology, Memory Center, North Hospital, University Hospital Center, CEDEX 2, 42055 Saint-Etienne, France.ORCID 0000-0002-9778-4918
Bernard LaurentDepartment of Neurology and Neuropsychology, Memory Center, North Hospital, University Hospital Center, CEDEX 2, 42055 Saint-Etienne, France.
Jean-Claude GetenetDepartment of Neurology and Neuropsychology, Memory Center, North Hospital, University Hospital Center, CEDEX 2, 42055 Saint-Etienne, France.ORCID 0000-0002-2856-7477
Anne BoulangéDepartment of Neurology and Neuropsychology, Memory Center, North Hospital, University Hospital Center, CEDEX 2, 42055 Saint-Etienne, France.
Aurelia Rendón de laCruzDepartment of Cognitive Psychology and Neuropsychology, University of Mons, 7000 Mons, Belgium.
Isabelle Simoes LoureiroDepartment of Cognitive Psychology and Neuropsychology, University of Mons, 7000 Mons, Belgium.
Laurent LefebvreDepartment of Cognitive Psychology and Neuropsychology, University of Mons, 7000 Mons, Belgium.ORCID 0000-0001-5123-9538
University of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The logopenic variant of primary progressive aphasia (lvPPA) shows different features from the non-fluent (nfvPPA) and semantic (svPPA) variants of PPA. Although language impairments remain the core symptoms, studies have highlighted the presence of executive disorders at the onset of the disease. Nevertheless, the results are contradictory, particularly in lvPPA. The aim of this study was to explore the executive profile of lvPPA. We compared executive functioning in lvPPA with the other two variants of PPA, Alzheimer's disease (AD) and a cognitively healthy group. In total, 70 patients with PPA, 32 patients with AD, and 41 healthy controls were included. They underwent a comprehensive executive battery assessing short-term and working memory, inhibition, flexibility, planning, and initiation. The analyses showed significant differences between the lvPPA group and the control group, except on visuospatial spans and the Stroop test, and between the lvPPA group and the other PPA groups and the AD group for several tasks. Thus, this research highlighted the existence of an executive dysfunction from the onset of the disease in lvPPA but also in the other two variants of PPA.

Indexed as

Alzheimer’s diseaseassessmentdiagnosisexecutive functionsprimary progressive aphasia

Identifiers

PMID36979216
PMCPMC10046635
OpenAlexW4322486486

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.