Evidence map›Paper›PMID 36979211›Full record

ArticleBrain sciences2023

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol.

Mylena Miki Lopes Ideta, Louise Makarem Oliveira, Daniel Buzaglo Gonçalves, Mylla Christie Paschoalino, Nise Alessandra Carvalho, Marcus Vinicius Della Coletta, Wellingson Paiva, Sérgio Brasil, Robson Luís Oliveira Amorim

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Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mylena Miki Lopes IdetaDepartment of Internal Medicine, Federal University of Amazonas, Manaus 69077, ZIP, Brazil.
Louise Makarem OliveiraDepartment of Neurology, University of São Paulo, Ribeirão Preto 14049, ZIP, Brazil.
Daniel Buzaglo GonçalvesDepartment of Internal Medicine, Federal University of Amazonas, Manaus 69077, ZIP, Brazil.ORCID 0000-0002-3243-970X
Mylla Christie PaschoalinoDepartment of Internal Medicine, Federal University of Amazonas, Manaus 69077, ZIP, Brazil.
Nise Alessandra CarvalhoDepartment of Internal Medicine, Federal University of Amazonas, Manaus 69077, ZIP, Brazil.
Marcus Vinicius Della ColettaDepartment of Neurology, Amazonas State University, Manaus 69005, ZIP, Brazil.
Wellingson PaivaDivision of Neurosurgery, Department of Neurology, University of São Paulo, São Paulo 01246, ZIP, Brazil.
Sérgio BrasilDivision of Neurosurgery, Department of Neurology, University of São Paulo, São Paulo 01246, ZIP, Brazil.
Robson Luís Oliveira AmorimDepartment of Internal Medicine, Federal University of Amazonas, Manaus 69077, ZIP, Brazil.ORCID 0000-0003-2391-7519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the importance of not mistaking when determining the brain death (BD) diagnostic, reliable confirmatory exams should be performed to enhance its security. This study aims to evaluate the intracranial pressure (ICP) pulse morphology behavior in brain-dead patients through a noninvasive monitoring system.

methodsA pilot case-control study was conducted in adults that met the BD national protocol criteria. Quantitative parameters from the ICP waveforms, such as the P2/P1 ratio, time-to-peak (TTP) and pulse amplitude (AMP) were extracted and analyzed comparing BD patients and health subjects.

resultsFifteen patients were included, and 6172 waveforms were analyzed. ICP waveforms presented substantial differences amidst BD patients when compared to the control group, especially AMP, which had lower values in patients diagnosed with BD (

conclusionsIn this exploratory study, noninvasive ICP waveforms have shown potential as a screening method in patients with suspected brain death. Future studies should be carried out in a larger population.

Indexed as

brain death diagnosisintracranial complianceintracranial pressure

Identifiers

PMID36979211
PMCPMC10046080

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