Evidence map›Paper›PMID 36979114›Full record

ArticleBiology2023

Uncovering the Gene Regulatory Network of Endothelial Cells in Mouse Duchenne Muscular Dystrophy: Insights from Single-Nuclei RNA Sequencing Analysis.

Yan Shen, Il-Man Kim, Mark Hamrick, Yaoliang Tang

Open access · goldFull text read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan ShenMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Il-Man KimAnatomy, Cell Biology, and Physiology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.ORCID 0000-0002-9268-8337
Mark HamrickMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Yaoliang TangMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-8372-1545
Augusta University · USIndiana University – Purdue University Indianapolis · US

Funding

Innovative Approaches to Treat Duchenne Muscular Dystrophy Using iPSC-Derived Muscle ProgenitorsR01AR070029 · NIAMS · AUGUSTA UNIVERSITY · PI ASHRAF, MUHAMMAD, TANG, YAO LIANG · 2016 to 2021
$2.6M
Identifying novel pathways targeting endothelial-to-mesenchymal transition during heart failureR01HL146481 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI KIM, IL-MAN · 2019 to 2022
$1.6M
American Heart Association-American Stroke Association 964856NHLBI NIH HHS R01 HL146481NIAMS NIH HHS R01 AR070029NIH HHS AR070029
6 · The paper itself

Abstract

introductionDuchenne muscular dystrophy (DMD) is a severe X-linked recessive disorder caused by mutations in the METHODS AND

resultsTo gain insights into the role of the

conclusionsOverall, this study provides new insights into the gene regulatory program in ECs in

Indexed as

cell metabolismDuchenne muscular dystrophydystrophinsingle-nuclear RNA sequencing (snRNA-seq)skeletal muscle-derived endothelial cells

Identifiers

PMID36979114
PMCPMC10045518
OpenAlexW4323846827

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read11
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.