Evidence map›Paper›PMID 36979077›Full record

ReviewBiology2023

Non-Invasive Assessment of Vascular Circulation Based on Flow Mediated Skin Fluorescence (FMSF).

Andrzej Marcinek, Joanna Katarzynska, Leslaw Sieron, Robert Skokowski, Jacek Zielinski, Jerzy Gebicki

Open access · goldFull text readReview
In one paragraph

Review in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Microvascular Dysfunction and Redox Imbalance in Long COVID.Microcirculation (New York, N.Y. : 1994) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Early peripheral perfusion monitoring in septic shock.European journal of medical research · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Assessment of NADH/NADSensors (Basel, Switzerland) · 2023
    Article
  15. Microcirculation and Mitochondria: The Critical Unit.Journal of clinical medicine · 2023
    Review
  16. Article
  17. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrzej MarcinekInstitute of Applied Radiation Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.ORCID 0000-0002-9852-7593
Joanna KatarzynskaAngionica Ltd., 90-924 Lodz, Poland.ORCID 0000-0002-3318-3443
Leslaw SieronAngionica Ltd., 90-924 Lodz, Poland.ORCID 0000-0002-7797-0262
Robert SkokowskiAngionica Ltd., 90-924 Lodz, Poland.
Jacek ZielinskiDepartment of Athletics, Strength and Conditioning, Poznan University of Physical Education, 61-871 Poznan, Poland.ORCID 0000-0002-2782-9973
Jerzy GebickiInstitute of Applied Radiation Chemistry, Lodz University of Technology, 90-924 Lodz, Poland.ORCID 0000-0003-2304-5036
Lodz University of Technology · PL

Funding

European Regional Development Fund under the Smart Growth Operational Program POIR. 01.01.01-00-0540/15-00
6 · The paper itself

Abstract

Flow Mediated Skin Fluorescence (FMSF) is a new non-invasive method for assessing vascular circulation and/or metabolic regulation. It enables assessment of both vasoconstriction and vasodilation. The method measures stimulation of the circulation in response to post-occlusive reactive hyperemia (PORH). It analyzes the dynamical changes in the emission of NADH fluorescence from skin tissue, providing the information on mitochondrial metabolic status and intracellular oxygen delivery through the circulatory system. Assessment of the vascular state using the FMSF technique is based on three parameters: reactive hyperemia response (RHR), hypoxia sensitivity (HS), and normoxia oscillatory index (NOI). The RHR and HS parameters determine the risk of vascular circulatory disorders and are the main diagnostic parameters. The NOI parameter is an auxiliary parameter for evaluating the state of microcirculation under stress of various origins (e.g., emotional stress, physical exhaustion, or post-infection stress). The clinical data show that the risk of vascular complications is limited among people whose RHR, log(HS), and NOI parameters are not significantly below the mean values determined by the FMSF technique, especially if they simultaneously meet the conditions RHR > 30% and log(HS) > 1.5 (HS > 30), and NOI > 60%.

Indexed as

flow mediated skin fluorescenceflowmotionFMSF techniqueHShypoxia sensitivitymicrocirculationNADH fluorescenceNOInormoxia oscillatory indexreactive hyperemia responseRHR

Identifiers

PMID36979077
PMCPMC10044925
OpenAlexW4322587924

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.