Evidence map›Paper›PMID 36979004›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile-The Example of

Patrycja Jakubek, Jovana Rajić, Monika Kuczyńska, Klaudia Suliborska, Mateusz Heldt, Karol Dziedziul, Melita Vidaković, Jacek Namieśnik, Agnieszka Bartoszek

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Plants (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Patrycja JakubekFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.ORCID 0000-0002-8517-387X
Jovana RajićInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.ORCID 0000-0002-2808-8484
Monika KuczyńskaFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.
Klaudia SuliborskaFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.
Mateusz HeldtFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.ORCID 0000-0003-2082-5715
Karol DziedziulFaculty of Applied Physics and Mathematics, Gdańsk University of Technology, 80-233 Gdańsk, Poland.ORCID 0000-0001-8015-3549
Melita VidakovićInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.ORCID 0000-0001-8410-6264
Jacek NamieśnikFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.
Agnieszka BartoszekFaculty of Chemistry, Gdańsk University of Technology, 80-233 Gdańsk, Poland.ORCID 0000-0002-6096-5838
Gdańsk University of Technology · PLUniversity of Belgrade · RSInstytut Biologii Doświadczalnej im. Marcelego Nenckiego · PL

Funding

European Cooperation in Science and Technology STSM Grant from CA16112Ministry of Science, Technological Development and Innovation of the Republic of Serbia Contract No. 451-03-47/2023-01/200007National Science Center 2014/14/A/ST4/00640
6 · The paper itself

Abstract

The role of catechins in the epigenetic regulation of gene expression has been widely studied; however, if and how this phenomenon relates to the redox properties of these polyphenols remains unknown. Our earlier study demonstrated that exposure of the human colon adenocarcinoma HT29 cell line to these antioxidants affects the expression of redox-related genes. In particular, treatment with (-)-epigallocatechin (EGC) downregulated transcription of gene encoding sulfiredoxin-1 (SRXN1), the peroxidase involved in the protection of cells against hydrogen peroxide-induced oxidative stress. The aim of this study was to investigate whether the observed

Indexed as

catechinsDNA methylationelectrochemistryepigeneticsreductive stresssulfiredoxin 1

Identifiers

PMID36979004
PMCPMC10045509
OpenAlexW4327949462

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read51
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.