Evidence map›Paper›PMID 36978969›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Ability of a Polyphenol-Rich Nutraceutical to Reduce Central Nervous System Lipid Peroxidation by Analysis of Oxylipins in Urine: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Raúl Arcusa, Juan Ángel Carillo, Begoña Cerdá, Thierry Durand, Ángel Gil-Izquierdo, Sonia Medina, Jean-Marie Galano, María Pilar Zafrilla, Javier Marhuenda

Open access · goldFull text read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Adrenic acid: A promising biomarker and therapeutic target (Review).International journal of molecular medicine · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Raúl ArcusaFaculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain.ORCID 0000-0002-4221-3528
Juan Ángel CarilloFaculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain.
Begoña CerdáFaculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain.ORCID 0000-0003-0385-1145
Thierry DurandInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR 5247, CNRS, Université de Montpellier, ENSCM 1919 Route de Mende, CEDEX 05, 34293 Montpellier, France.ORCID 0000-0001-6086-7296
Ángel Gil-IzquierdoResearch Group on Quality Safety and Bioactivity of Plant Foods, Food Science and Technology Department, CEBAS-CSIC, 30100 Murcia, Spain.ORCID 0000-0001-7646-0386
Sonia MedinaResearch Group on Quality Safety and Bioactivity of Plant Foods, Food Science and Technology Department, CEBAS-CSIC, 30100 Murcia, Spain.ORCID 0000-0002-7231-6480
Jean-Marie GalanoInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR 5247, CNRS, Université de Montpellier, ENSCM 1919 Route de Mende, CEDEX 05, 34293 Montpellier, France.
María Pilar ZafrillaFaculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain.ORCID 0000-0002-1463-7120
Javier MarhuendaFaculty of Health Sciences, Universidad Católica de San Antonio, 30107 Murcia, Spain.
Universidad Católica de Murcia · ESCentro de Edafología y Biología Aplicada del Segura · ESÉcole Nationale Supérieure de Chimie de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isoprostanes (IsoPs) are lipid peroxidation biomarkers that reveal the oxidative status of the organism without specifying which organs or tissues it occurs in. Similar compounds have recently been identified that can assess central nervous system (CNS) lipid peroxidation status, usually oxidated by reactive oxygen species. These compounds are the neuroprostanes (NeuroPs) derived from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and the F

Indexed as

lipid peroxidationoxylipinspolyphenols

Identifiers

PMID36978969
PMCPMC10045327
OpenAlexW4324358210

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read6
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.