ReviewBioengineering (Basel, Switzerland)2023
Recent Advances in Coupled MBS and FEM Models of the Spine-A Review.
Review in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Advances in Musculoskeletal Modeling of the Thoraco-Lumbar Spine: A Comprehensive Systematic Review.Annals of biomedical engineering · 2025Pooled it
- Methods for assessing core muscle co-activation in the lumbar region: a narrative review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Automated Setup of CT-Based Vertebral Finite Element Simulations: Quantifying the Influence of Boundary-Condition Components on Fracture-Load Estimates.Annals of biomedical engineering · 2026Article
- Sequentially coupled musculoskeletal multibody and finite element simulation for biomechanical modeling of the human masticatory system.Frontiers in bioengineering and biotechnology · 2026Article
- Finite element analysis of mandibular fracture fixation authenticated by 3D printed mandible mechanical testing.Scientific reports · 2025Article
- A Muscle-Driven Spine Model for Predictive Simulations in the Design of Spinal Implants and Lumbar Orthoses.Bioengineering (Basel, Switzerland) · 2025Article
- CT-based surrogate parameters for MRI-based disc height and endplate degeneration in the lumbar spine.BMC medical imaging · 2024Article
- Biomechanical assessment of mandibular fracture fixation using finite element analysis validated by polymeric mandible mechanical testing.Scientific reports · 2024Article
- Uniting disciplines for a modern take: exploring the science behind manual therapies.The Journal of manual & manipulative therapy · 2024Article
- From MRI to FEM: an automated pipeline for biomechanical simulations of vertebrae and intervertebral discs.Frontiers in bioengineering and biotechnology · 2024Article
- Musculoskeletal spine modeling in large patient cohorts: how morphological individualization affects lumbar load estimation.Frontiers in bioengineering and biotechnology · 2024Article
- Advances in Biomechanics-Based Motion Analysis.Bioengineering (Basel, Switzerland) · 2023Article
- Muscle-driven forward dynamic active hybrid model of the lumbosacral spine: combined FEM and multibody simulation.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
How back pain is related to intervertebral disc degeneration, spinal loading or sports-related overuse remains an unanswered question of biomechanics. Coupled MBS and FEM simulations can provide a holistic view of the spine by considering both the overall kinematics and kinetics of the spine and the inner stress distribution of flexible components. We reviewed studies that included MBS and FEM co-simulations of the spine. Thereby, we classified the studies into unidirectional and bidirectional co-simulation, according to their data exchange methods. Several studies have demonstrated that using unidirectional co-simulation models provides useful insights into spinal biomechanics, although synchronizing the two distinct models remains a key challenge, often requiring extensive manual intervention. The use of a bidirectional co-simulation features an iterative, automated process with a constant data exchange between integrated subsystems. It reduces manual corrections of vertebra positions or reaction forces and enables detailed modeling of dynamic load cases. Bidirectional co-simulations are thus a promising new research approach for improved spine modeling, as a main challenge in spinal biomechanics is the nonlinear deformation of the intervertebral discs. Future studies will likely include the automated implementation of patient-specific bidirectional co-simulation models using hyper- or poroelastic intervertebral disc FEM models and muscle forces examined by an optimization algorithm in MBS. Applications range from clinical diagnosis to biomechanical analysis of overload situations in sports and injury prediction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.