ReviewAntibiotics (Basel, Switzerland)2023
Acute Cholecystitis from Biliary Lithiasis: Diagnosis, Management and Treatment.
Review in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Prospective randomized trial of triple port laparoscopic cholecystectomy combined with choledochoscopic common bile duct exploration and primary closure for acute abdominal pain.Scientific reports · 2026Trial
- Biliary stent migration after cholecystectomy following a single-preoperative ERCP: insights into real-world bile duct management.Surgical endoscopy · 2026Article
- Histological, ultrastructural, and single-cell profiling reveal immune-mediated remodeling in gallbladder inflammation.Cell and tissue research · 2026Article
- Article
- Effect of enhanced recovery after surgery nursing on gastrointestinal recovery function and life quality in patients laparoscopic cholecystectomy.World journal of gastrointestinal surgery · 2025Article
- Article
- Risk factors for and a prediction nomogram of physical frailty in older patients hospitalized with acute calculous cholecystitis.Global health & medicine · 2025Article
- Textbook outcome and associated risk factors in laparoscopic transcystic common bile duct exploration.World journal of gastroenterology · 2025Article
- Global burden of gallbladder and biliary diseases (1990-2021) with healthcare workforce analysis and projections to 2035.BMC gastroenterology · 2025Article
- The Value of Systemic Inflammatory Index and Nutritional Marker in Predicting Acute Calculus Cholecystitis and Its Severity.Journal of inflammation research · 2025Article
- Research progress on the role of microbiota in the pathogenesis of gallstone disease.Frontiers in microbiology · 2025Review
- Article
- Percutaneous transhepatic papillary ballooning and extraction for common bile duct stones: a single-center experience.Quantitative imaging in medicine and surgery · 2024Article
- Updates on Antibiotic Regimens in Acute Cholecystitis.Medicina (Kaunas, Lithuania) · 2024Review
- Altered microbiome of serum exosomes in patients with acute and chronic cholecystitis.BMC microbiology · 2024Article
- The value of preoperative neutrophil/lymphocyte ratio in predicting the severity of cholecystolithiasis with cholecystitis in elderly patients.BMC surgery · 2023Article
- Severe acute cholecystitis successfully treated with endoscopic nasobiliary drainage tube insertion: A case report.SAGE open medical case reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biliary lithiasis is a global disorder affecting nearly 20% of the world's population, although most cases occur without symptoms. Gallbladder stones could move into the common bile duct after gallbladder contraction, causing acute cholecystitis. The progression of the acute disease can take different forms, from mild inflammation, treatable with oral antibiotics, to the most severe forms with septic shock or biliary peritonitis, requiring specific treatment. Liver function tests and abdominal ultrasound are generally sufficient for diagnostic purposes. The most commonly used antibiotic is penicillin, with piperacillin achieving the best results; alternatively, fluoroquinolones could also be used, although there is no univocal consensus and surgery remains the only definitive treatment. A prolonged antibiotic therapy after cholecystectomy seems inadvisable, except in severe cases and/or in the immuno-compromised patient, where it should be periodically evaluated to avoid antibiotic resistance and unnecessary use. This review presents an evidence-based analysis to describe the advantages and disadvantages of the available options for the treatment of biliary lithiasis and cholecystitis, from the pathophysiological mechanisms behind lithiasis formation and also covering the main diagnostic findings for biliary stones, recommending an approach tailored to the patient's characteristics and to the team's expertise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.