ArticleBMC cancer2023
Residual fibroglandular breast tissue after mastectomy is associated with an increased risk of a local recurrence or a new primary breast cancer".
Article in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for residual fibroglandular breast tissue following a mastectomy - an overview and retrospective cohort study.BMC cancer · 2024Pooled it
- Detection of residual fibroglandular tissue on breast MRI and associated factors in women treated with mastectomy and DIEP flap breast reconstruction.Insights into imaging · 2026Article
- Prepectoral Versus Retropectoral Implant-Based Breast Reconstruction-Considerations Regarding the Implant Pocket.Journal of clinical medicine · 2026Article
- Factors associated with local breast cancer recurrence after mastectomy in the Netherlands: a retrospective nationwide cohort study.Breast (Edinburgh, Scotland) · 2026Article
- Clinical Outcomes of Lipodermal Flaps in One-Stage Pre-pectoral Implant-Based Breast Reconstruction with Wise-Pattern Mastectomy: A Single-Center Experience.Aesthetic plastic surgery · 2026Article
- Assessment of treatment outcomes in patients with breast cancer who underwent mastectomy and breast reconstruction with sparing of the areola-nipple complex - single-center analysis.Frontiers in oncology · 2026Article
- Article
- Mastectomy Flap Thickness Required for Successful Nipple Preservation, Mastopexy, and Reconstruction in Ptotic Breasts.Plastic and reconstructive surgery. Global open · 2025Article
- Ipsilateral Breast Carcinoma Recurrence: True Recurrence or New Primary? A Clinicopathologic and Molecular Study.The American journal of surgical pathology · 2025Article
- Clinical factors influencing residual subcutaneous tissue after skin-sparing and nipple-sparing mastectomy with immediate breast reconstruction.Frontiers in oncology · 2025Article
- Postoperative Outcomes of Pre-Pectoral Versus Sub-Pectoral Implant Immediate Breast Reconstruction.Cancers · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResidual fibroglandular breast tissue (RFGT) following a mastectomy has been claimed to be associated with the occurrence of an in-breast local recurrence (IBLR) or new primary tumor (NP). Yet, scientific evidence proving this assumption is lacking. The primary aim of the study was to verify whether RFGT following a mastectomy is a risk factor for an IBLR or NP.
methodsThis retrospective analysis included all patients that underwent a mastectomy and were followed up at the Department of Obstetrics and Gynecology of the Medical University of Vienna between 01.01.2015 and 26.02.2020. RFGT volume (assessed on magnetic resonance imaging) was correlated with the prevalence of an IBLR and a NP.
resultsA total of 105 patients (126 breasts) following a therapeutic mastectomy were included. After a mean follow-up of 46.0 months an IBLR had occurred in 17 breasts and a NP in 1 breast. A significant difference in RFGT volume was observed between the disease-free cohort and the subgroup with an IBLR or NP (p = .017). A RFGT volume of ≥ 1153 mm
conclusionsRFGT volume is associated with an increased risk for an IBLR or NP.
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