Evidence map›Paper›PMID 36977988›Full record

ReviewBMC emergency medicine2023

War-related traumatic brain injuries during the Syrian armed conflict in Damascus 2014-2017: a cohort study and a literature review.

Ibrahem Hanafi, Eskander Munder, Sulafa Ahmad, Iman Arabhamo, Suzan Alziab, Noor Badin, Ahmad Omarain, Mhd Khaled Jawish, Muhannad Saleh, Vera Nickl and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in BMC emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. War-related traumatic brain injury in Gaza: a multi-center prospective analysis of patterns and outcomes.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Ibrahem HanafiDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Damascus University, Mazzah, Damascus, Syria. Ibrahem.W.Hanafi@gmail.com.ORCID 0000-0001-5306-0128
Eskander MunderFaculty of Medicine, Syrian Private University, Mazzah, Damascus, Syria.ORCID 0000-0003-1941-9947
Sulafa AhmadFaculty of Medicine, Damascus University, Mazzah, Damascus, Syria.ORCID 0000-0002-3563-0657
Iman ArabhamoFaculty of Medicine, Syrian Private University, Mazzah, Damascus, Syria.ORCID 0000-0003-1382-9822
Suzan AlziabFaculty of Medicine, Damascus University, Mazzah, Damascus, Syria.ORCID 0000-0003-3313-5019
Noor BadinFaculty of Medicine, Damascus University, Mazzah, Damascus, Syria.ORCID 0000-0002-3844-952X
Ahmad OmarainFaculty of Medicine, Damascus University, Mazzah, Damascus, Syria.ORCID 0000-0003-0071-0195
Mhd Khaled JawishFaculty of Medicine, Damascus University, Mazzah, Damascus, Syria.ORCID 0000-0003-1952-2813
Muhannad SalehDivision of Neurosurgery, Department of Surgery, Damascus Hospital, Damascus, Syria.ORCID 0000-0001-9075-9667
Vera NicklDepartment of Neurosurgery, Würzburg University, Würzburg, Germany.ORCID 0000-0003-4232-1673
Tamara WipplingerDepartment of Neurosurgery, Würzburg University, Würzburg, Germany.ORCID 0000-0003-2326-049X
Christoph WipplingerDepartment of Neurosurgery, Würzburg University, Würzburg, Germany.ORCID 0000-0002-9001-6932
Robert NicklDepartment of Neurosurgery, Würzburg University, Würzburg, Germany.ORCID 0000-0002-0108-5494
Damascus University · SYUniversity of Würzburg · DESyrian Private University · SYDamascus Hospital · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe decade-long Syrian armed conflict killed or injured more than 11% of the Syrian population. Head and neck injuries are the most frequent cause of war-related trauma, about half of which are brain injuries. Reports about Syrian brain trauma victims were published from neighboring countries; However, none are available from Syrian hospitals. This study aims to report war-related traumatic brain injuries from the Syrian capital.

methodsWe conducted a retrospective cohort study between 2014 and 2017 at Damascus Hospital, the largest public hospital in Damascus, Syria. Target patients were the victims of combat-related traumatic brain injuries who arrived alive and were admitted to the neurosurgery department or to another department but followed by the neurosurgery team. The collected data included the mechanism, type, and site of injury based on imaging findings; types of invasive interventions; intensive-care unit (ICU) admissions; as well as neurological status at admission and discharge including several severity scales.

resultsOur sample consisted of 195 patients; Ninety-six of them were male young adults, in addition to 40 females and 61 children. Injuries were caused by shrapnel in 127 (65%) cases, and by gunshots in the rest, and most of them (91%) were penetrating. Sixty-eight patients (35%) were admitted to the ICU, and 56 (29%) underwent surgery. Neurological impairment was reported in 49 patients (25%) at discharge, and the mortality rate during hospitalization was 33%. Mortality and neurological impairment associated significantly with higher values on clinical and imaging severity scores.

conclusionsThis study captured the full spectrum of war-related brain injuries of civilians and armed personnel in Syria without the delay required to transport patients to neighboring countries. Although the clinical presentation of injuries at admission was not as severe as that in previous reports, the inadequate resources (i.e., ventilators and operation rooms) and the lack of previous experience with similar injuries might have resulted in the higher mortality rate. Clinical and imaging severity scales can provide a handy tool in identifying cases with low probability of survival especially with the shortage of personal and physical resources.

Indexed as

Brain Injuries, TraumaticWar-Related InjuriesArmed ConflictsChildCohort StudiesFemaleHumansMaleRetrospective StudiesSyriaYoung AdultBrain injuryCombat injuryExplosion injuryGunshot injuryNeurological injurySyrian armed conflictWar-related injury

Identifiers

PMID36977988
PMCPMC10053936
OpenAlexW4361216278

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.