Evidence map›Paper›PMID 36977929›Full record

ArticleBioprocess and biosystems engineering2023

Potential use of bio functionalized nanoparticles to attenuate triple negative breast cancer (MDA-MB-231 cells).

Murali Santhoshkumar, Dhandapani Perumal, Jayaraman Narenkumar, Vasudevan Ramachandran, Karnan Muthusamy, Ahmed Alfarhan, Ernest David

Abstract read
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In one paragraph

Article in Bioprocess and biosystems engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Murali SanthoshkumarDepartment of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, Tamilnadu, 632115, India.
Dhandapani PerumalEnvironmental Molecular Microbiology Research Laboratory, Department of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, Tamilnadu, 632115, India.
Jayaraman NarenkumarCentre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, Tamil Nadu, 600073, India. narencherry77@gmail.com.
Vasudevan RamachandranDepartment of Medical Science and Technology, University College of MAIWP International, Taman Batu Muda, Batu Caves, 68100, Kuala Lumpur, Malaysia.
Karnan MuthusamyGrassland and Forages Division, Rural Development Administration, National Institute of Animal Science, Cheonan, 31000, Korea.
Ahmed AlfarhanDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
Ernest DavidDepartment of Biotechnology, Thiruvalluvar University, Serkadu, Vellore, Tamilnadu, 632115, India. Ernestdavid2002@yahoo.com.

Funding

Researchers Supporting Project RSP 2022/11
6 · The paper itself

Abstract

This study showed that bio-functional silver nanoparticles (AgNPs) and zinc oxide nanoparticles (ZnONPs) were synthesized in aqueous extracts of Gymnema sylvestre leaves and tested for toxicity assessment against triple-negative breast cancer cells (TNBC). Biofunctional nanoparticle (NPs) samples were characterized using UV-Vis spectroscopy, FT-IR, XRD, SEM, and TEM. The results showed that the phytofabrication of AgNPs resulted in a dark brown, UV-vis maximum absorbance peak at 413 nm. The AgNPs were crystalline and spherical, with sizes ranging from 20 to 60 nm, as confirmed by the XRD pattern and TEM images. Another phytofabrication of ZnONPs exhibited a white precipitate corresponding to a UV-Vis maximum absorption peak at 377 nm and a fine micro flower morphology with a particle-sized tribution between 100 and 200 nm. In addition, FT-IR spectra showed that bioorganic compounds are associated with NPs that respond to reduced Ag

Indexed as

Metal NanoparticlesTriple Negative Breast NeoplasmsZinc OxideAnti-Bacterial AgentsCell Line, TumorHumansMDA-MB-231 CellsPlant ExtractsSilverSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsPlant ExtractsSilverZinc OxideAgNPsGymnema sylvestreToxicityTriple-negative breast cancerZnONPs

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.