Evidence map›Paper›PMID 36977910›Full record

ArticleJournal of ophthalmic inflammation and infection2023

Central retinal vein occlusion associated with Bartonella henselae infection.

Sunil Bellur, Amir Ali, Nam V Nguyen, Joshua K Fernandes, Shilpa Kodati

Open access · goldFull text read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Demography, clinical profile and risk of retinal vein occlusion among patients with age-related macular degeneration - a tertiary hospital based study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sunil BellurNational Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N248, Bethesda, Maryland, 20892, USA.
Amir AliNational Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N248, Bethesda, Maryland, 20892, USA.
Nam V NguyenNational Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N248, Bethesda, Maryland, 20892, USA.
Joshua K FernandesDC Retina, Silver Spring, Maryland, USA.
Shilpa KodatiNational Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N248, Bethesda, Maryland, 20892, USA. shilpa.kodati@nih.gov.
National Institutes of Health · USNational Eye Institute · US

Funding

Studies of Ocular inflammation: Translational ResearchZIAEY000556 · NEI · NATIONAL EYE INSTITUTE · PI CASPI, RACHEL R. · 2017 to 2025
$11.3M
6 · The paper itself

Abstract

purposeTo report the clinical features and treatment course of a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae (B. henselae) infection. OBSERVATION: A 36-year-old male was evaluated for unilateral vision loss. He denied prodromal symptoms but reported prior exposure to fleas. Best corrected visual acuity (BCVA) was 20/400 in the left eye. Clinical examination revealed a CRVO with atypical features including significant peripapillary exudates and peripheral vascular sheathing. Laboratory testing revealed elevated B. henselae IgG titers (1:512) with no abnormalities on hypercoagulability testing. The patient was treated with doxycycline and aflibercept with an excellent clinical response and improvement in BCVA to 20/25 in the left eye two months later.

conclusionCRVO is a rare but sight-threatening complication of ocular bartonellosis and can be the presenting sign of infection, even in the absence of cat exposure or prodromal symptoms.

Indexed as

Bartonella henselaeCat scratch diseaseCentral retinal vein occlusionMacular edemaOcular bartonellosisVasculitis

Identifiers

PMID36977910
PMCPMC10050272
OpenAlexW4361207311

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read17
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.