Evidence map›Paper›PMID 36977894›Full record

ArticlePflugers Archiv : European journal of physiology2023

Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity.

Johannes Loffing, Vladimir Pech, Dominique Loffing-Cueni, Delaney C Abood, Young Hee Kim, Chao Chen, Truyen D Pham, Jill W Verlander, Susan M Wall

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Intercalated Cell ClC-K2 Channel Contributes to Systemic ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Johannes Loffing *Institute of Anatomy, University of Zurich, Zurich, Switzerland. johannes.loffing@anatomy.uzh.ch.
Vladimir Pech *Division of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA.
Dominique Loffing-CueniInstitute of Anatomy, University of Zurich, Zurich, Switzerland.
Delaney C AboodDivision of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA.
Young Hee KimDivision of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA.
Chao ChenThe Division of Nephrology, Hypertension and Renal Transplantation, The University of Florida College of Medicine, Gainesville, FL, USA.
Truyen D PhamDivision of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA.
Jill W VerlanderThe Division of Nephrology, Hypertension and Renal Transplantation, The University of Florida College of Medicine, Gainesville, FL, USA.
Susan M WallDivision of Renal Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA. smwall@emory.edu.
Emory University · USUniversity of Zurich · CHFlorida College · USUniversity of Florida · US

Funding

Regulation of intercalated cell function by the mineralocorticoid receptorR01DK119793 · NIDDK · EMORY UNIVERSITY · PI WALL, SUSAN MARIE · 2019 to 2022
$1.6M
NIDDK NIH HHS R01 DK119793
6 · The paper itself

Abstract

The intercalated cell Cl

Indexed as

AldosteroneAnion Transport ProteinsAnimalsBlood PressureEpithelial Sodium ChannelsMiceRatsSulfate TransportersAldosteroneAnion Transport ProteinsEpithelial Sodium ChannelsSulfate TransportersAldosteroneENaCIntercalated cellsPendrin

Identifiers

PMID36977894
PMCPMC10105674
OpenAlexW4361288534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.