Evidence map›Paper›PMID 36977757›Full record

ArticleCommunications biology2023

Global motion processing in infants' visual cortex and the emergence of autism.

Irzam Hardiansyah, Pär Nyström, Mark J Taylor, Sven Bölte, Angelica Ronald, Terje Falck-Ytter

Open access · goldFull text read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sleep in Young Children With Autism, ADHD and Combined Presentations.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  2. Visual function and autism spectrum disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Irzam HardiansyahCenter of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Department of Women's and Children's Health, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden. irzam.hardiansyah@ki.se.ORCID 0000-0003-2529-9697
Pär NyströmUppsala Child and Baby Lab, Department of Psychology, Uppsala University, Uppsala, Sweden.
Mark J TaylorDepartment of Medical Epidemiology & Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Sven BölteCenter of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Department of Women's and Children's Health, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden.ORCID 0000-0002-4579-4970
Angelica RonaldDepartment of Psychological Sciences, Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK.ORCID 0000-0002-9576-2176
Terje Falck-YtterCenter of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Department of Women's and Children's Health, Karolinska Institutet & Stockholm Health Care Services, Stockholm, Sweden. terje.falck-ytter@psyk.uu.se.ORCID 0000-0001-9714-0197
Karolinska Institutet · SEUppsala University · SEBirkbeck, University of London · GBCurtin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism is a heritable and common neurodevelopmental condition, with behavioural symptoms typically emerging around age 2 to 3 years. Differences in basic perceptual processes have been documented in autistic children and adults. Specifically, data from many experiments suggest links between autism and alterations in global visual motion processing (i.e., when individual motion information is integrated to perceive an overall coherent pattern). Yet, no study has investigated whether a distinctive organization of global motion processing precede the emergence of autistic symptoms in early childhood. Here, using a validated infant electroencephalography (EEG) experimental paradigm, we first establish the normative activation profiles for global form, global motion, local form, and local motion in the visual cortex based on data from two samples of 5-month-old infants (total n = 473). Further, in a sample of 5-month-olds at elevated likelihood of autism (n = 52), we show that a different topographical organization of global motion processing is associated with autistic symptoms in toddlerhood. These findings advance the understanding of neural organization of infants' basic visual processing, and its role in the development of autism.

Indexed as

Autistic DisorderVisual CortexAdultChildChild, PreschoolElectroencephalographyHumansInfantMotionVisual Perception

Identifiers

PMID36977757
PMCPMC10050234
OpenAlexW4361285038

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read28
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.